Family-Based versus Unrelated Case-Control Designs for Genetic Associations

• Evangelos Evangelou,

  Affiliation Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece

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• Thomas A Trikalinos,

  Affiliations Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece , Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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• Georgia Salanti,

  Affiliation Biostatistics Unit, Medical Research Council, Cambridge, United Kingdom

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• John P. A Ioannidis

  *To whom correspondence should be addressed. E-mail: jioannid@cc.uoi.gr

  Affiliations Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece , Institute for Clinical Research and Health Policy Studies, Tufts University School of Medicine, Boston, Massachusetts, United States of America , Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece

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