Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

Fergal M. Waldron; Graham N. Stone; Darren J. Obbard

doi:10.1371/journal.pgen.1007533

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Peer-reviewed

Research Article

Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

Fergal M. Waldron ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: fergal.waldron@ed.ac.uk

Affiliation Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom

http://orcid.org/0000-0003-2622-0776

⨯
Graham N. Stone,

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – review & editing

Affiliation Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom
⨯
Darren J. Obbard

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom, Centre for Immunity Infection and Evolution, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom

http://orcid.org/0000-0001-5392-8142

⨯

Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

Fergal M. Waldron,
Graham N. Stone,
Darren J. Obbard

Published: July 30, 2018
https://doi.org/10.1371/journal.pgen.1007533

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Hen1 Methylation of miRNAs in Cnidaria

Posted by DarrenObbard on 20 Aug 2018 at 08:10 GMT

In this manuscript we note that miRNAs are likely to be 3' 2'-0-methylated in the cnidarian, "Actinia equina". We fail to note that this had previously been shown for "Nematostella" miRNAs by Grimson et al (2008; Supplementary table 1), and we apologise for not drawing attention to this.

Grimson A, Srivastava M, Fahey B, Woodcroft BJ, Chiang HR, et al. (2008) Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals. Nature 455: 1193–1197. pmid:18830242 https://doi.org/10.1038/n...

Competing interests declared: I am an author of the present manuscript

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Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

Metagenomic sequencing suggests a diversity of RNA interference-like responses to viruses across multicellular eukaryotes

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Hen1 Methylation of miRNAs in Cnidaria

Posted by DarrenObbard on 20 Aug 2018 at 08:10 GMT