Regulatory Network Analyses Reveal Genome-Wide Potentiation of LIF Signaling by Glucocorticoids and Define an Innate Cell Defense Response

Open Access

Peer-reviewed

Research Article

David Langlais,

Affiliation Laboratoire de Génétique Moléculaire, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Quebec, Canada
⨯
Catherine Couture,

Affiliation Laboratoire de Génétique Moléculaire, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Quebec, Canada
⨯
Aurélio Balsalobre ,

* E-mail: aurelio.balsalobre@ircm.qc.ca (AB); jacques.drouin@ircm.qc.ca (JD)

Affiliation Laboratoire de Génétique Moléculaire, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Quebec, Canada
⨯
Jacques Drouin

* E-mail: aurelio.balsalobre@ircm.qc.ca (AB); jacques.drouin@ircm.qc.ca (JD)

Affiliation Laboratoire de Génétique Moléculaire, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, Quebec, Canada
⨯

Reader Comments

biological replicates of each condition were hybridized on Affymetrix MOE 430 2.0 arrays, except for Dex 18 h that was hybridized on the previous version of MOE A and B arrays
http://plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000224#article1.body1.sec4.sec6.p1

The complete expression arrays data are available on the NCBI GEO web site (#GSE19042).

No competing interests declared.

Gene regulation
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Mammalian genomics
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Genetic loci
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Pituitary gland
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Binding analysis
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Gene expression
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Sequence motif analysis
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DNA transcription
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