PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex

Ci Fu; Joseph Heitman

doi:10.1371/journal.pgen.1007113

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Open Access

Peer-reviewed

Research Article

PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex

Ci Fu,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States of America
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Joseph Heitman

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: heitm001@duke.edu

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States of America
⨯

PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex

Ci Fu,
Joseph Heitman

Published: November 27, 2017
https://doi.org/10.1371/journal.pgen.1007113

About the Authors

Ci Fu

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States of America

Joseph Heitman

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: heitm001@duke.edu

Affiliation Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, United States of America

Competing Interests

The authors have declared that no competing interests exist.

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Cell fusion
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Cryptococcus neoformans
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Membrane fusion
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Cryptococcus
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Bisexuals
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Cell membranes
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Saccharomyces cerevisiae
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Membrane proteins
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