About the Authors

Wakana Ohashi

Affiliations RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan

Shunsuke Kimura

Affiliation Laboratory of Histology and Cytology, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

Toshihiko Iwanaga

Affiliation Laboratory of Histology and Cytology, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

Yukihiro Furusawa

Affiliations Division of Biochemistry, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan, Division of Mucosal Barriology, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

Tarou Irié

Affiliation Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Shinagawa-ku, Tokyo, Japan

Hironori Izumi

Affiliation Department of Molecular Neuroscience, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan

Takashi Watanabe

Affiliation Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan

Atsushi Hijikata

Affiliation Nagahama Institute of Bio-Science and Technology, Tamura, Nagahama, Shiga, Japan

Takafumi Hara

Affiliation Molecular and Cellular Physiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro, Tokushima, Japan

Osamu Ohara

Affiliations Laboratory for Integrative Genomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, Department of Technology Development, Kazusa DNA Research Institute, Kisarazu, Chiba, Japan

Haruhiko Koseki

Affiliation Laboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan

Toshiro Sato

Affiliation Department of Gastroenterology, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan

Sylvie Robine

Affiliation Equipe de Morphogenese et Signalisation cellulaires UMR 144 CNRS/Institut Curie, Paris, France

Hisashi Mori

Affiliation Department of Molecular Neuroscience, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan

Yuichi Hattori

Affiliation Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Sugitani, Toyama, Japan

Hiroshi Watarai

Affiliation Division of Stem Cell Cellomics, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

Kenji Mishima

Affiliation Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Shinagawa-ku, Tokyo, Japan

Hiroshi Ohno

Affiliation Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan

Koji Hase

hase-kj@pha.keio.ac.jp (KH); fukada@ph.bunri-u.ac.jp (TF)

Affiliations Division of Biochemistry, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan, Division of Mucosal Barriology, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

Toshiyuki Fukada

hase-kj@pha.keio.ac.jp (KH); fukada@ph.bunri-u.ac.jp (TF)

Affiliations RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan, Division of Pathology, Department of Oral Diagnostic Sciences, School of Dentistry, Showa University, Shinagawa-ku, Tokyo, Japan, Molecular and Cellular Physiology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro, Tokushima, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceptualization: WO KH TF. Data curation: WO KH TF. Formal analysis: WO KH TF. Funding acquisition: WO HM KH TF. Investigation: WO SK TIw YF TIr HI TW AH TH HM. Methodology: WO KH TF. Project administration: KH TF. Resources: OO HK TS SR YH HW KM HO KH TF. Supervision: TS HO OO HK KH TF. Validation: WO SK TIw YF KH TF. Visualization: WO KH TF. Writing – original draft: WO KH TF. Writing – review & editing: WO KH TF.