About the Authors

Samuel E. Jones

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Jessica Tyrrell

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Andrew R. Wood

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Robin N. Beaumont

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Katherine S. Ruth

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Marcus A. Tuke

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Hanieh Yaghootkar

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Youna Hu

Affiliations 23andMe Inc., Mountain View, California, United States of America, A9.com Inc, Palo Alto, California, United States of America

Maris Teder-Laving

Affiliation Estonian Genome Center and Institute of Molecular and Cell Biology of University of Tartu, Estonian Biocentre, Tartu, Estonia

Caroline Hayward

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland

Till Roenneberg

Affiliation Institute of Medical Psychology, Ludwig-Maximilians-University, Munich, Germany

James F. Wilson

Affiliations Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland

Fabiola Del Greco

Affiliation Center for Biomedicine, European Academy of Bolzano, Bozen, Italy–affiliated Institute of the University of Lübeck, Lübeck, Germany

Andrew A. Hicks

Affiliation Center for Biomedicine, European Academy of Bolzano, Bozen, Italy–affiliated Institute of the University of Lübeck, Lübeck, Germany

Chol Shin

Affiliations Division of Pulmonary, Sleep and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea, Institute of Human Genomic Study, College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea

Chang-Ho Yun

Affiliation Department of Neurology, Bundang Clinical Neuroscience Institute, Seoul National University Bundang Hospital, Seongnam, Republic of Korea

Seung Ku Lee

Affiliation Institute of Human Genomic Study, College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea

Andres Metspalu

Affiliation Estonian Genome Center and Institute of Molecular and Cell Biology of University of Tartu, Estonian Biocentre, Tartu, Estonia

Enda M. Byrne

Affiliation The University of Queensland, Queensland Brain Institute, Brisbane, Australia

Philip R. Gehrman

Affiliation Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Henning Tiemeier

Affiliations Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands, Department of Psychiatry, Erasmus Medical Center, Rotterdam, Netherlands

Karla V. Allebrandt

Affiliation Institute of Medical Psychology, Ludwig-Maximilians-University, Munich, Germany

Rachel M. Freathy

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Anna Murray

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

David A. Hinds

Affiliation 23andMe Inc., Mountain View, California, United States of America

Timothy M. Frayling

Contributed equally to this work with: Timothy M. Frayling, Michael N. Weedon

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Michael N. Weedon

Contributed equally to this work with: Timothy M. Frayling, Michael N. Weedon

M.N.Weedon@exeter.ac.uk

Affiliation Genetics of Complex Traits, University of Exeter Medical School, Exeter, United Kingdom

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: DH and YH are current or former employees of and own stock or stock options in 23andMe, Inc. There are no other competing interests.

Author Contributions

Conceived and designed the experiments: SEJ TMF MNW. Performed the experiments: SEJ JT ARW RNB KSR MAT HY RMF AMu TMF MNW MTL CH TR JFW FDG AAH CS CHY SKL AMe EMB PRG HT. Analyzed the data: SEJ JT ARW RNB KSR MAT HY RMF AMu TMF MNW. Wrote the paper: SEJ JT ARW RNB KSR MAT HY YH MTL CH TR JFW FDG AAH CS CHY SKL AMe EMB PRG HT KVA RMF AMu DAH TMF MNW.