About the Authors

Seungyeul Yoo

Affiliations Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Sachiko Takikawa

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Mount Sinai School of Medicine, New York, New York, United States of America

Patrick Geraghty

Affiliation Department of Medicine, St. Luke's Roosevelt Medical Center, Mount Sinai School of Medicine, New York, New York, United States of America

Carmen Argmann

Affiliations Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Joshua Campbell

Affiliation Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

Luan Lin

Affiliations Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Tao Huang

Affiliations Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Zhidong Tu

Affiliations Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Robert Feronjy

Affiliation Department of Medicine, St. Luke's Roosevelt Medical Center, Mount Sinai School of Medicine, New York, New York, United States of America

Avrum Spira

Affiliation Division of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

Eric E. Schadt

Affiliations Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Charles A. Powell

Affiliation Division of Pulmonary, Critical Care and Sleep Medicine, Mount Sinai School of Medicine, New York, New York, United States of America

Jun Zhu

jun.zhu@mssm.edu

Affiliations Institute of Genomics and Multiscale Biology, Mount Sinai School of Medicine, New York, New York, United States of America, Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SY JZ. Performed the experiments: SY ST PG RF CAP JZ. Analyzed the data: SY ST CA JC TH ZT AS CAP EES JZ. Contributed reagents/materials/analysis tools: PG JC LL TH ZT RF AS. Wrote the paper: SY CA EES JZ.