About the Authors
- Monisha E. Nongpiur
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Contributed equally to this work with: Monisha E. Nongpiur, Chiea Chuen Khor, Hongyan Jia
Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Chiea Chuen Khor
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Contributed equally to this work with: Monisha E. Nongpiur, Chiea Chuen Khor, Hongyan Jia
Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Infectious Diseases, Genome Institute of Singapore, Singapore, Human Genetics, Genome Institute of Singapore, Singapore, Department of Paediatrics, National University Health System & National University of Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Hongyan Jia
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Contributed equally to this work with: Monisha E. Nongpiur, Chiea Chuen Khor, Hongyan Jia
Affiliation Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China
- Belinda K. Cornes
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Li-Jia Chen
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Affiliation Department of Ophthalmology & Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China
- Chunyan Qiao
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Affiliation Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China
- K. Saidas Nair
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Affiliation Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America
- Ching-Yu Cheng
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Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
- Liang Xu
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Affiliation Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
- Ronnie George
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Affiliation Vision Research Foundation, Sankara Nethralaya, Chennai, India
- Do Tan
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Affiliation Vietnam National Institute of Ophthalmology, Hanoi, Vietnam
- Khaled Abu-Amero
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Affiliation Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
- Shamira A. Perera
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Mineo Ozaki
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Affiliation Ozaki Eye Hospital, Hyuga, Japan
- Takanori Mizoguchi
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Affiliation Mizoguchi Eye Clinic, Sasebo, Japan
- Yasuo Kurimoto
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Affiliation Kobe Gen Hospital, Kobe, Japan
- Sancy Low
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Affiliation NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom
- Liza-Sharmini A. Tajudin
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Affiliation Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia
- Ching-Lin Ho
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Clement C. Y. Tham
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Affiliation Department of Ophthalmology & Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China
- Ileana Soto
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Affiliation Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America
- Paul T. K. Chew
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Affiliation Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
- Hon-Tym Wong
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Affiliation Department of Ophthalmology, Tan Tock Seng Hospital, Singapore
- Balekudaru Shantha
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Affiliation Vision Research Foundation, Sankara Nethralaya, Chennai, India
- Masako Kuroda
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Affiliation Kobe Gen Hospital, Kobe, Japan
- Essam A. Osman
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Affiliation Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
- Guangxian Tang
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Affiliation Xingtai Eye Hospital, Xingtai, China
- Sujie Fan
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Affiliation Handan Eye Hospital, Handan, China
- Hailin Meng
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Affiliation Anyang Eye Hospital, Anyang, China
- Hua Wang
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Affiliation Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China
- Bo Feng
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Affiliation Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China
- Victor H. K. Yong
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Serena M. L. Ting
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Yang Li
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Affiliation Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
- Ya-Xing Wang
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Affiliation Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China
- Zheng Li
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Raghavan Lavanya
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Ren-Yi Wu
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Ying-Feng Zheng
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Daniel H. Su
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Seng-Chee Loon
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Affiliation Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
- R. Rand Allingham
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Affiliation Duke University Medical Center, Durham, North Carolina, United States of America
- Michael A. Hauser
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Affiliation Duke University Medical Center, Durham, North Carolina, United States of America
- Nagaswamy Soumittra
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Affiliation Vision Research Foundation, Sankara Nethralaya, Chennai, India
- Vedam L. Ramprasad
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Affiliation Vision Research Foundation, Sankara Nethralaya, Chennai, India
- Naushin Waseem
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Affiliation NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom
- Azhany Yaakub
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Affiliation Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia
- Kee-Seng Chia
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Affiliation Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
- Govindasamy Kumaramanickavel
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Affiliation Vision Research Foundation, Sankara Nethralaya, Chennai, India
- Tina T. Wong
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Alicia C. How
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Affiliation Singapore Eye Research Institute and Singapore National Eye Centre, Singapore
- Tran Nguyen Bich Chau
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Affiliation Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
- Cameron P. Simmons
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Affiliations Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom
- Jin-Xin Bei
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Affiliations State Key Laboratory of Oncology in Southern China, Guangzhou, China, Department of Experimental Research, Sun Yat-Sen University Cancer Centre, Guangzhou, China
- Yi-Xin Zeng
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Affiliations State Key Laboratory of Oncology in Southern China, Guangzhou, China, Department of Experimental Research, Sun Yat-Sen University Cancer Centre, Guangzhou, China, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China
- Shomi S. Bhattacharya
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Affiliation NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom
- Mingzhi Zhang
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Affiliation Shantou University/Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou, China
- Donald T. Tan
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Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
- Yik-Ying Teo
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Affiliations Human Genetics, Genome Institute of Singapore, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Saleh A. Al-Obeidan
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Affiliation Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
- Do Nhu Hon
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Affiliation Vietnam National Institute of Ophthalmology, Hanoi, Vietnam
- E-Shyong Tai
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Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Department of Medicine, National University Health System & National University of Singapore, Singapore
- Seang-Mei Saw
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Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore
- Paul J. Foster
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Affiliation NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, United Kingdom
- Lingam Vijaya
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Affiliation Vision Research Foundation, Sankara Nethralaya, Chennai, India
- Jost B. Jonas
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Affiliation Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Germany
- Tien-Yin Wong
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Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
- Simon W. M. John
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Affiliation Howard Hughes Medical Institute, The Jackson Laboratory, Bar Harbor, Maine, United States of America
- Chi-Pui Pang
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¶These authors jointly directed this work.
Affiliation Department of Ophthalmology & Visual Sciences, the Chinese University of Hong Kong, Hong Kong, China
- Eranga N. Vithana
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¶These authors jointly directed this work.
Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
- Ningli Wang
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* E-mail: wningli@vip.163.com (NW); aung.tin@snec.com.sg (TA)
¶These authors jointly directed this work.
Affiliations Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing, China, Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
- Tin Aung
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* E-mail: wningli@vip.163.com (NW); aung.tin@snec.com.sg (TA)
¶These authors jointly directed this work.
Affiliations Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Department of Ophthalmology, National University Health System & National University of Singapore, Singapore
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: TA ENV CCK MEN NiW. Performed the experiments: LJC KSN IS BS MEN VHKY SMLT ZL MZ. Analyzed the data: CCK HJ BKC TNBC CPS JXB YXF YXZ SWMJ. Contributed reagents/materials/analysis tools: HJ CQ CYC MK RL RYW YFZ SCL RRA MAH VLR NaW KSC GK SSB DTT YYT EST SMS JBJ. Wrote the paper: CCK ENV MEN TA SWMJ. Clinicians responsible for obtaining informed consent and enrolling study participants: LX RG TD KAA SAP MO TM YK SL LSAT CLH CCYT PTKC HTW BS EAO GT SF HM HW BF YL YXW DHS NS AY TTW ACH. Site principal investigators for their respective sample collections: SAAO DNH PJF LV TYW CPP NiW TA. Lead coordinators for sample collection: CQ MEN RG LJC TD KAA SL MZ LSAT.