About the Authors

Irene Hernando-Herraez

Affiliation Institute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain

Javier Prado-Martinez

Affiliation Institute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain

Paras Garg

Affiliation Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai School, New York, New York, United States of America

Marcos Fernandez-Callejo

Affiliation Institute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain

Holger Heyn

Affiliation Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain

Christina Hvilsom

Affiliation Research and Conservation, Copenhagen Zoo, Frederiksberg, Denmark

Arcadi Navarro

Affiliations Institute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain, Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain

Manel Esteller

Affiliations Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain, Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain, Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain

Andrew J. Sharp

Contributed equally to this work with: Andrew J. Sharp, Tomas Marques-Bonet

andrew.sharp@mssm.edu (AJS); tomas.marques@upf.edu (TMB)

Affiliation Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai School, New York, New York, United States of America

Tomas Marques-Bonet

Contributed equally to this work with: Andrew J. Sharp, Tomas Marques-Bonet

andrew.sharp@mssm.edu (AJS); tomas.marques@upf.edu (TMB)

Affiliations Institute of Evolutionary Biology (UPF-CSIC), PRBB, Barcelona, Spain, Catalan Institution of Research and Advanced Studies (ICREA), Barcelona, Spain

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TMB AJS IHH. Performed the experiments: IHH JPM. Analyzed the data: IHH ME HH TMB AJS JPM. Contributed reagents/materials/analysis tools: MFC PG CH AN. Wrote the paper: IHH TMB AJS.