About the Authors

Jesse D. Riordan

Affiliation Department of Anatomy and Cell Biology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Vincent W. Keng

Current address: Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong

Affiliation Masonic Cancer Center, Department of Genetics, Cell Biology and Development and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

Barbara R. Tschida

Affiliation Masonic Cancer Center, Department of Genetics, Cell Biology and Development and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

Todd E. Scheetz

Affiliation Center for Bioinformatics and Computational Biology, Department of Opthalmology and Visual Sciences, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Jason B. Bell

Affiliation Department of Genetics, Cell Biology and Development and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

Kelly M. Podetz-Pedersen

Affiliation Department of Genetics, Cell Biology and Development and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

Catherine D. Moser

Affiliation Division of Gastroenterology and Hepatology, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America

Neal G. Copeland

Affiliation Cancer Research Program, The Methodist Hospital Research Institute, Houston, Texas, United States of America

Nancy A. Jenkins

Affiliation Cancer Research Program, The Methodist Hospital Research Institute, Houston, Texas, United States of America

Lewis R. Roberts

Affiliation Division of Gastroenterology and Hepatology, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America

David A. Largaespada

Affiliation Masonic Cancer Center, Department of Genetics, Cell Biology and Development and Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America

Adam J. Dupuy

adam-dupuy@uiowa.edu

Affiliation Department of Anatomy and Cell Biology, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JDR VWK DAL AJD. Performed the experiments: JDR VWK BRT JBB KMP-P. Analyzed the data: JDR VWK TES AJD. Contributed reagents/materials/analysis tools: CDM NGC NAJ LRR. Wrote the paper: JDR AJD.