About the Authors

Lavinia Paternoster

Contributed equally to this work with: Lavinia Paternoster, Mattias Lorentzon, Terho Lehtimäki, Joel Eriksson

Affiliations MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Mattias Lorentzon

Contributed equally to this work with: Lavinia Paternoster, Mattias Lorentzon, Terho Lehtimäki, Joel Eriksson

Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Terho Lehtimäki

Contributed equally to this work with: Lavinia Paternoster, Mattias Lorentzon, Terho Lehtimäki, Joel Eriksson

Affiliation Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere and Tampere University Hospital, Tampere, Finland

Joel Eriksson

Contributed equally to this work with: Lavinia Paternoster, Mattias Lorentzon, Terho Lehtimäki, Joel Eriksson

Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Mika Kähönen

Affiliation Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland

Olli Raitakari

Affiliations Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland, Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland

Marika Laaksonen

Affiliation Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland

Harri Sievänen

Affiliation The UKK Institute for Health Promotion Research, Tampere, Finland

Jorma Viikari

Affiliation Department of Medicine, University of Turku and Turku University Hospital, Turku, Finland

Leo-Pekka Lyytikäinen

Affiliation Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere and Tampere University Hospital, Tampere, Finland

Dan Mellström

Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Magnus Karlsson

Affiliation Clinical and Molecular Osteoporosis Research Unit, Department of Orthopaedics, Lund University, Skane University Hospital, Malmö, Sweden

Östen Ljunggren

Affiliation Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden

Elin Grundberg

Affiliations Department of Human Genetics, McGill University, Montreal, Canada, McGill University and Genome Quebec Innovation Centre, Montreal, Canada

John P. Kemp

Affiliations MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Adrian Sayers

Affiliations School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

Maria Nethander

Affiliation Genomics Core Facility, University of Gothenburg, Gothenburg, Sweden

David M. Evans

These authors also contributed equally to this work.

Affiliations MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

Liesbeth Vandenput

These authors also contributed equally to this work.

Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Jon H. Tobias

These authors also contributed equally to this work.

Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

Claes Ohlsson

claes.ohlsson@medic.gu.se

These authors also contributed equally to this work.

Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: L Paternoster, M Lorentzon, T Lehtimäki, M Kähönen, M Laaksonen, H Sievänen, J Viikari, D Mellström, E Grundberg, M Karlsson, DM Evans, L Vandenput, JH Tobias, C Ohlsson. Performed the experiments: L Paternoster, E Grundberg, M Lorentzon, T Lehtimäki, M Kähönen, O Raitakari, J Viikari, M Laaksonen, L Vandenput, C Ohlsson. Analyzed the data: L Paternoster, T Lehtimäki, J Eriksson, L-P Lyytikäinen, JP Kemp, A Sayers, M Nethander, C Ohlsson. Contributed reagents/materials/analysis tools: M Lorentzon, T Lehtimäki, J Eriksson, O Raitakari, E Grundberg, Ö Ljunggren, M Laaksonen, H Sievänen, J Viikari, L-P Lyytikäinen, D Mellström, M Karlsson, JP Kemp, DM Evans, JH Tobias, C Ohlsson. Wrote the paper: L Paternoster, DM Evans, L Vandeput, JH Tobias, C Ohlsson.