About the Authors

Fan Liu

Affiliation Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Fedde van der Lijn

Affiliations Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Medical Informatics, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Radiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Claudia Schurmann

Affiliation Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany

Gu Zhu

Affiliation Queensland Institute of Medical Research, Brisbane, Australia

M. Mallar Chakravarty

Affiliations Rotman Research Institute, University of Toronto, Toronto, Canada, Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada

Pirro G. Hysi

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Andreas Wollstein

Affiliation Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Oscar Lao

Affiliation Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Marleen de Bruijne

Affiliations Department of Medical Informatics, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Radiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

M. Arfan Ikram

Affiliations Department of Radiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Aad van der Lugt

Affiliation Department of Radiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Fernando Rivadeneira

Affiliations Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

André G. Uitterlinden

Affiliations Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Albert Hofman

Affiliation Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Wiro J. Niessen

Affiliations Department of Medical Informatics, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Radiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, Department of Imaging Science and Technology, Faculty of Applied Sciences, Delft University of Technology, Delft, The Netherlands

Georg Homuth

Affiliation Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany

Greig de Zubicaray

Affiliation Centre for Advanced Imaging, University of Queensland, Brisbane, Australia

Katie L. McMahon

Affiliation Centre for Advanced Imaging, University of Queensland, Brisbane, Australia

Paul M. Thompson

Affiliation Laboratory of Neuroimaging, School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Amro Daboul

Affiliation Center of Oral Health, Department of Prosthodontics, Gerostomatology, and Dental Materials, University Medicine Greifswald, Greifswald, Germany

Ralf Puls

Affiliation Department of Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany

Katrin Hegenscheid

Affiliation Department of Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany

Liisa Bevan

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Zdenka Pausova

Affiliation The Hospital of Sick Children, University of Toronto, Toronto, Canada

Sarah E. Medland

Affiliation Queensland Institute of Medical Research, Brisbane, Australia

Grant W. Montgomery

Affiliation Queensland Institute of Medical Research, Brisbane, Australia

Margaret J. Wright

Affiliation Queensland Institute of Medical Research, Brisbane, Australia

Carol Wicking

Affiliation Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

Stefan Boehringer

Affiliation Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands

Timothy D. Spector

Affiliation Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Tomáš Paus

Affiliations Rotman Research Institute, University of Toronto, Toronto, Canada, Montréal Neurological Institute, McGill University, Montréal, Canada

Nicholas G. Martin

Affiliation Queensland Institute of Medical Research, Brisbane, Australia

Reiner Biffar

Affiliation Center of Oral Health, Department of Prosthodontics, Gerostomatology, and Dental Materials, University Medicine Greifswald, Greifswald, Germany

Manfred Kayser

m.kayser@erasmusmc.nl

Affiliation Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands

Competing Interests

TS and MK have consulted for Identitas Inc. and are on the SAB but without financial or other direct benefits. All other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FL MK. Analyzed the data: FL FvdL CS GZ MMC AW OL SB. Contributed reagents/materials/analysis tools: MK RB NGM TP TDS AH AGU MAI. Data preparation: FvdL PGH MdB AW MAI AvdL FR AGU AH WJN GH GdZ KLM PMT AD RP KH LB ZP SEM GWM MJW TDS TP NGM RB. Wrote the manuscript: FL MK. Additional contributions: CW FvdL AW NGM CS MMC OL MAI SB TDS TP RB. Approved the manuscript: FL FvdL CS GZ MMC PGH AW OL MdB MAI AvdL FR AGU AH WJN GH GdZ KLM PMT AD RP KH LB ZP SEM GWM MJW CW SB TDS TP NGM RB MK.