About the Authors
- Eimear E. Kenny
-
Current address: Department of Genetics, Stanford University School of Medicine, Stanford, California, United States of America
Affiliation Department of Computer Sciences, Columbia University, New York, New York, United States of America
- Itsik Pe'er
-
Affiliation Department of Computer Sciences, Columbia University, New York, New York, United States of America
- Amir Karban
-
Affiliation Department of Gastroenterology, Rambam Health Care Campus, B. Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
- Laurie Ozelius
-
Affiliation Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
- Adele A. Mitchell
-
Affiliation Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
- Sok Meng Ng
-
Affiliation Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut, United States of America
- Monica Erazo
-
Affiliation Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
- Harry Ostrer
-
Affiliation Department of Pathology, Albert Einstein College of Medicine, New York, New York, United States of America
- Clara Abraham
-
Affiliation Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut, United States of America
- Maria T. Abreu
-
Affiliation Division of Gastroenterology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
- Gil Atzmon
-
Affiliation Genetic Core for Longevity, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, United States of America
- Nir Barzilai
-
Affiliation Genetic Core for Longevity, Institute for Aging Research and the Diabetes Research Center, Albert Einstein College of Medicine, Bronx, New York, United States of America
- Steven R. Brant
-
Affiliations Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
- Susan Bressman
-
Affiliations Mirken Department of Neurology, Beth Israel Medical Center, New York, New York, United States of America, The Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, United States of America
- Edward R. Burns
-
Affiliation Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, United States of America
- Yehuda Chowers
-
Affiliation Department of Gastroenterology, Rambam Health Care Campus, B. Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
- Lorraine N. Clark
-
Affiliation Department of Pathology and Cell Biology, Columbia University, New York, New York, United States of America
- Ariel Darvasi
-
Affiliation The Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem, Israel
- Dana Doheny
-
Affiliation Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
- Richard H. Duerr
-
Affiliations Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
- Rami Eliakim
-
Affiliation Department of Gastroenterology and Hepatology, Sheba Medical Center, Raman Gan, Israel
- Nir Giladi
-
Affiliation Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel
- Peter K. Gregersen
-
Affiliation Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute for Medical Research, North Shore LIJ Health System, Manhasset, New York, United States of America
- Hakon Hakonarson
-
Affiliation Center for Applied Genomics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
- Michelle R. Jones
-
Affiliation Division of Endocrinology, Diabetes, and Metabolism, Graduate Program in Biomedical Sciences and Translational Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
- Karen Marder
-
Affiliations Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
- Dermot P. B. McGovern
-
Affiliations Department of Translational Medicine, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America, Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
- Jennifer Mulle
-
Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
- Avi Orr-Urtreger
-
Affiliation Genetic Institute, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel-Aviv, Israel
- Deborah D. Proctor
-
Affiliation Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut, United States of America
- Ann Pulver
-
Affiliations Epidemiology-Genetics Program in Schizophrenia, Bipolar Disorders, and Related Disorders, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
- Jerome I. Rotter
-
Affiliation Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
- Mark S. Silverberg
-
Affiliation IBD Group, Mount Sinai Hospital, University of Toronto, Toronto, Canada
- Thomas Ullman
-
Affiliation Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
- Stephen T. Warren
-
Affiliations Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America, Departments of Biochemistry and Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States of America
- Matti Waterman
-
Affiliation Department of Gastroenterology, Rambam Health Care Campus, B. Rappaport Institute for Research in the Medical Sciences, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
- Wei Zhang
-
Affiliation Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut, United States of America
- Aviv Bergman
-
Affiliation Department of Systems and Computational Biology, Albert Einstein College of Medicine, New York, New York, United States of America
- Lloyd Mayer
-
Affiliation Division of Gastroenterology, Department of Medicine, Mount Sinai School of Medicine, New York, New York, United States of America
- Seymour Katz
-
Affiliation Albert Einstein College of Medicine, North Shore University Hospital-Long Island Jewish Hospital Systems, St. Francis Hospital, Great Neck, New York, United States of America
- Robert J. Desnick
-
Affiliation Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
- Judy H. Cho
-
* E-mail: judy.cho@yale.edu (JH Cho) (JC); inga.peter@mssm.edu (I Peter) (IP)
Affiliation Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut, United States of America
- Inga Peter
-
* E-mail: judy.cho@yale.edu (JH Cho) (JC); inga.peter@mssm.edu (I Peter) (IP)
Affiliation Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: I Peter, JH Cho, I Pe'er, EE Kenny, RJ Desnick. Performed the experiments: AA Mitchell, M Erazo, SM Ng, PK Gregersen, J Mulle. Analyzed the data: EE Kenny, I Pe'er, MR Jones, DPB McGovern. Contributed reagents/materials/analysis tools: A Karban, L Ozelius, H Ostrer, C Abraham, MT Abreu, G Atzmon, N Barzilai, SR Brant, S Bressman, ER Burns, Y Chowers, LN Clark, D Doheny, RH Duerr, R Eliakim, N Giladi, H Hakonarson, K Marder, DPB McGovern, A Orr-Urtreger, A Darvasi, DD Proctor, A Pulver JI Roter, MS Silverberg, T Ullman, ST Warren, M Waterman, W Zhang, A Bergman, L Mayer, S Katz, JH Cho, I Peter. Wrote the paper: I Peter, JH Cho, I Pe'er, EE Kenny.