About the Authors

Rudolf S. N. Fehrmann

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Ritsert C. Jansen

Contributed equally to this work with: Ritsert C. Jansen, Jan H. Veldink, Harm-Jan Westra

Affiliation Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands

Jan H. Veldink

Contributed equally to this work with: Ritsert C. Jansen, Jan H. Veldink, Harm-Jan Westra

Affiliation Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands

Harm-Jan Westra

Contributed equally to this work with: Ritsert C. Jansen, Jan H. Veldink, Harm-Jan Westra

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Danny Arends

Affiliation Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands

Marc Jan Bonder

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Jingyuan Fu

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Patrick Deelen

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Harry J. M. Groen

Affiliation Department of Pulmonology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Asia Smolonska

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Rinse K. Weersma

Affiliations Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands, Department of Gastroenterology and Hepatology, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands

Robert M. W. Hofstra

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Wim A. Buurman

Affiliation NUTRIM School for Nutrition, Toxicology, and Metabolism, Department of General Surgery, Maastricht University Medical Center, Maastricht, The Netherlands

Sander Rensen

Affiliation NUTRIM School for Nutrition, Toxicology, and Metabolism, Department of General Surgery, Maastricht University Medical Center, Maastricht, The Netherlands

Marcel G. M. Wolfs

Affiliation Department of Pathology and Medical Biology, Medical Biology Section, Molecular Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Mathieu Platteel

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Alexandra Zhernakova

Affiliation Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands

Clara C. Elbers

Affiliation Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Eleanora M. Festen

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Gosia Trynka

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Marten H. Hofker

Affiliation Department of Pathology and Medical Biology, Medical Biology Section, Molecular Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Christiaan G. J. Saris

Affiliation Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands

Roel A. Ophoff

Affiliations Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands, Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands, Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California, United States of America

Leonard H. van den Berg

Affiliation Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands

David A. van Heel

Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

Cisca Wijmenga

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Gerard J. te Meerman

These authors also contributed equally to this work.

Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands

Lude Franke

lude@ludesign.nl

These authors also contributed equally to this work.

Affiliations Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LF GJtM. Performed the experiments: MP AS CGJS MGMW HJMG LHvdB RAO RKW. Analyzed the data: RSNF LF GJtM H-JW RCJ JHV AS. Contributed reagents/materials/analysis tools: RSNF H-JW GJtM RCJ LF CW DAvH LHvdB RAO RKW MHH DA MJB PD JF RMWH WAB SR AZ CCE EMF GT. Wrote the paper: RSNF LF GJtM RCJ CW MHH DAvH.