Disease-Associated Mutations That Alter the RNA Structural Ensemble

Matthew Halvorsen; Joshua S. Martin; Sam Broadaway; Alain Laederach

doi:10.1371/journal.pgen.1001074

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Open Access

Peer-reviewed

Research Article

Disease-Associated Mutations That Alter the RNA Structural Ensemble

Matthew Halvorsen,

Affiliation Biomedical Sciences Department, University at Albany, Albany, New York, United States of America
⨯
Joshua S. Martin,

Affiliation Developmental Genetics and Bioinformatics, Wadsworth Center, Albany, New York, United States of America
⨯
Sam Broadaway,

Affiliation Developmental Genetics and Bioinformatics, Wadsworth Center, Albany, New York, United States of America
⨯
Alain Laederach

* E-mail: alain@wadsworth.org

Affiliations Biomedical Sciences Department, University at Albany, Albany, New York, United States of America, Developmental Genetics and Bioinformatics, Wadsworth Center, Albany, New York, United States of America
⨯

Disease-Associated Mutations That Alter the RNA Structural Ensemble

Matthew Halvorsen,
Joshua S. Martin,
Sam Broadaway,
Alain Laederach

Published: August 19, 2010
https://doi.org/10.1371/journal.pgen.1001074

About the Authors

Matthew Halvorsen

Affiliation Biomedical Sciences Department, University at Albany, Albany, New York, United States of America

Joshua S. Martin

Affiliation Developmental Genetics and Bioinformatics, Wadsworth Center, Albany, New York, United States of America

Sam Broadaway

Affiliation Developmental Genetics and Bioinformatics, Wadsworth Center, Albany, New York, United States of America

Alain Laederach

* E-mail: alain@wadsworth.org

Affiliations Biomedical Sciences Department, University at Albany, Albany, New York, United States of America, Developmental Genetics and Bioinformatics, Wadsworth Center, Albany, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MH AL. Performed the experiments: MH JSM. Analyzed the data: MH JSM SB. Wrote the paper: MH JSM AL.

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Untranslated regions
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Single nucleotide polymorphisms
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RNA structure
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Human genomics
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Internal ribosome entry site
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Mutation
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Messenger RNA
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RNA analysis
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