About the Authors
- Jennifer K. Lowe
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Affiliations The Rockefeller University, New York, New York, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America
- Julian B. Maller
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Current address: Department of Statistics, University of Oxford, Oxford, United Kingdom
Affiliations Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America
- Itsik Pe'er
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Current address: Department of Computer Science, Columbia University, New York, New York, United States of America
Affiliations Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America
- Benjamin M. Neale
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Affiliations Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, United Kingdom
- Jacqueline Salit
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Affiliation The Rockefeller University, New York, New York, United States of America
- Eimear E. Kenny
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Affiliation The Rockefeller University, New York, New York, United States of America
- Jessica L. Shea
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Affiliations Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America
- Ralph Burkhardt
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Affiliation The Rockefeller University, New York, New York, United States of America
- J. Gustav Smith
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Affiliation Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America
- Weizhen Ji
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Affiliation Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Martha Noel
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Affiliation The Rockefeller University, New York, New York, United States of America
- Jia Nee Foo
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Affiliation Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Maude L. Blundell
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Affiliation The Rockefeller University, New York, New York, United States of America
- Vita Skilling
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Current address: Department of Health, Education, and Social Affairs, Federated States of Micronesia, Palikir, Pohnpei, Federated States of Micronesia
Affiliation Kosrae Department of Health Services, Kosrae, Federated States of Micronesia
- Laura Garcia
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Affiliation The Rockefeller University, New York, New York, United States of America
- Marcia L. Sullivan
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Affiliation The Rockefeller University, New York, New York, United States of America
- Heather E. Lee
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Affiliation The Rockefeller University, New York, New York, United States of America
- Anna Labek
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Affiliation The Rockefeller University, New York, New York, United States of America
- Hope Ferdowsian
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Affiliation The Rockefeller University, New York, New York, United States of America
- Steven B. Auerbach
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Affiliation Department of Health and Human Services, Heath Resources and Services Administration, New York, New York, United States of America
- Richard P. Lifton
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Affiliations Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
- Christopher Newton-Cheh
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Affiliations Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Jan L. Breslow
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Affiliation The Rockefeller University, New York, New York, United States of America
- Markus Stoffel
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Current address: Institute of Molecular Systems Biology, Swiss Federal Institute of Technology (ETH), Zurich, Switzerland
Affiliation The Rockefeller University, New York, New York, United States of America
- Mark J. Daly
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Affiliations Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- David M. Altshuler
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* E-mail: altshuler@molbio.mgh.harvard.edu (DMA); friedj@rockefeller.edu (JMF)
Affiliations Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
- Jeffrey M. Friedman
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* E-mail: altshuler@molbio.mgh.harvard.edu (DMA); friedj@rockefeller.edu (JMF)
Affiliations The Rockefeller University, New York, New York, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: JKL JBM IP BMN VS JLB MS MJD DMA JMF. Performed the experiments: JKL JBM IP JS JLS MLB VS LG MLS HEL. Analyzed the data: JKL JBM BMN JS EEK JGS CNC MJD DMA. Contributed reagents/materials/analysis tools: JKL JBM IP BMN JS EEK JLS RB JGS WJ MN JNF MLB LG AL HF SBA RPL CNC JLB MS MJD JMF. Wrote the paper: JKL JGS CNC DMA.