Targeting the X Chromosome during Spermatogenesis Induces Y Chromosome Transmission Ratio Distortion and Early Dominant Embryo Lethality in Anopheles gambiae

Nikolai Windbichler; Philippos Aris Papathanos; Andrea Crisanti

doi:10.1371/journal.pgen.1000291

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Peer-reviewed

Research Article

Targeting the X Chromosome during Spermatogenesis Induces Y Chromosome Transmission Ratio Distortion and Early Dominant Embryo Lethality in Anopheles gambiae

Nikolai Windbichler ,

Contributed equally to this work with: Nikolai Windbichler, Philippos Aris Papathanos

Affiliation Faculty of Life Science, Imperial College London, London, United Kingdom
⨯
Philippos Aris Papathanos ,

Contributed equally to this work with: Nikolai Windbichler, Philippos Aris Papathanos

Affiliation Faculty of Life Science, Imperial College London, London, United Kingdom
⨯
Andrea Crisanti

* E-mail: acrs@imperial.ac.uk

Affiliation Faculty of Life Science, Imperial College London, London, United Kingdom
⨯

Targeting the X Chromosome during Spermatogenesis Induces Y Chromosome Transmission Ratio Distortion and Early Dominant Embryo Lethality in Anopheles gambiae

Nikolai Windbichler,
Philippos Aris Papathanos,
Andrea Crisanti

Published: December 5, 2008
https://doi.org/10.1371/journal.pgen.1000291

About the Authors

Nikolai Windbichler

Contributed equally to this work with: Nikolai Windbichler, Philippos Aris Papathanos

Affiliation Faculty of Life Science, Imperial College London, London, United Kingdom

Philippos Aris Papathanos

Contributed equally to this work with: Nikolai Windbichler, Philippos Aris Papathanos

Affiliation Faculty of Life Science, Imperial College London, London, United Kingdom

Andrea Crisanti

* E-mail: acrs@imperial.ac.uk

Affiliation Faculty of Life Science, Imperial College London, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NW PAP. Performed the experiments: NW PAP. Analyzed the data: NW PAP. Contributed reagents/materials/analysis tools: PAP. Wrote the paper: NW AC. Initiated the project: NW. Supervised and inspired the project: AC.

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Sperm
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Embryos
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Mosquitoes
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Testes
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X chromosomes
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Heterozygosity
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Y chromosomes
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Larvae
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