About the Authors

Hong Lan

Contributed equally to this work with: Hong Lan, Meng Chen

Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Meng Chen

Contributed equally to this work with: Hong Lan, Meng Chen

Affiliation Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America

Jessica B Flowers

Affiliations Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America , Department of Nutritional Sciences, University of Wisconsin, Madison, Wisconsin, United States of America

Brian S Yandell

Affiliations Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America , Department of Horticulture, University of Wisconsin, Madison, Wisconsin, United States of America

Donnie S Stapleton

Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Christine M Mata

Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Eric Ton-Keen Mui

Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Matthew T Flowers

Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Kathryn L Schueler

Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Kenneth F Manly

Affiliation Departments of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

Robert W Williams

Affiliation Departments of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America

Christina Kendziorski

Affiliation Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin, United States of America

Alan D Attie

To whom correspondence should be addressed. E-mail: attie@biochem.wisc.edu

Affiliation Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

HL, JBF, BSY, MTF, CK, and ADA conceived and designed the experiments. HL, JBF, DSS, ETKM, MTF, and KLS performed the experiments. HL, MC, JBF, BSY, CMM, MTF, CK, and ADA analyzed the data. HL, JBF, BSY, KFM, and RWW contributed reagents/materials/analysis tools. HL, MC, JBF, BSY, CK, and ADA wrote the paper.