Table of Contents

March 2006

A novel gammaretrovirus, XMRV, has been identified in a set of tumor samples from patients with prostate cancer. XMRV was found almost exclusively in prostates of men homozygous for a common RNase L variant, R462Q, previously associated with increased risk of prostate cancer (see Urisman et al).

Image Credit: XMRV-infected stromal cells are detected in prostate tumor sections by fluorescence in situ hybridization. Green represents XMRV nucleic acid, and blue represents DAPI-stained nuclei. Photo by Ross J. Molinaro.



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