Why do we have a vaccine for measles, but not cytomegalovirus (CMV)?

Mark R. Schleiss, Sallie R. Permar, Stanley A. Plotkin

PLOS Pathogens: published May 4, 2026 | https://doi.org/10.1371/journal.ppat.1014136

Tracking fungal pathogens on cancer: Oncomicrobes or opportunistic bystanders?

Rosana Alves, Wouter Van Genechten, Patrick Van Dijck

PLOS Pathogens: published May 7, 2026 | https://doi.org/10.1371/journal.ppat.1014179

How post-translational modifications in pathogenic fungi inform pathogenesis and immune responses

Satya Ranjan Sahu, Charles A. Specht, Stuart M. Levitz

PLOS Pathogens: published May 8, 2026 | https://doi.org/10.1371/journal.ppat.1014162

Flipping the script: Using mucosal immune obstacles to inform vaccine design

Avan Antia, Siyuan Ding

PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014230

Decoding the complex receptor landscape of enterovirus D68

Mengyang Zhao, Leiliang Zhang

PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014231

Positioning HIV SMRTcap within the HIV reservoir toolbox

Anthony Loddo, Pierre Delobel, Camille Vellas

PLOS Pathogens: published May 29, 2026 | https://doi.org/10.1371/journal.ppat.1014257

How resistance-nodulation-division (RND) efflux pumps contribute to virulence

Corrella S. Detweiler, Ilyas Alav

PLOS Pathogens: published May 14, 2026 | https://doi.org/10.1371/journal.ppat.1014228

The Nipah virus threat in India: Epidemiological trends, risk drivers, and lessons for pandemic preparedness

Apoorva, Sunit K. Singh

PLOS Pathogens: published May 20, 2026 | https://doi.org/10.1371/journal.ppat.1014226

SARS-CoV-2 Nsp1 suppresses the canonical NF-κB pathway by promoting ubiquitin-dependent degradation of TAK1 kinase

Han-cheng Wei, Qingxin Yang, Hong Yang, Yu-hang Wang, Kai Wang, Kepan Linghu, Natacha S. Ogando, Xiaoya Huang, Eric J. Snijder, Yu Zhong, Yu Chen, Quan Yuan, Lu Chen, Jing-wen Lin

PLOS Pathogens: published May 4, 2026 | https://doi.org/10.1371/journal.ppat.1014191

PGRP-LA regulates peritrophic matrix synthesis and influences trypanosome infection outcomes in tsetse flies

Aurélien Vigneron, Brian L. Weiss, Yuebiao Feng, Jingwen Wang, Erick Awuoche, Hang Nguyen, Alessandra Orfano, Liu Yang, Emre Aksoy, Serap Aksoy

PLOS Pathogens: published May 4, 2026 | https://doi.org/10.1371/journal.ppat.1013520

Characterization of atypical Ebola virus disease in ferrets

Wenguang Cao, Shihua He, Helene Schulz, Jordan Wight, Michael Chan, Karla Emeterio, Guodong Liu, Jonathan Audet, Kevin Tierney, Kimberly Azaransky, Kathy Frost, Lilianne Gee, Peter McQueen, Patrick Chong, Sarah B. Sulkosky, Stephanie Booth, Garrett Westmacott, Erica Ollmann Saphire, Xiankun Zeng, Logan Banadyga

PLOS Pathogens: published May 4, 2026 | https://doi.org/10.1371/journal.ppat.1013916

Staphylococcus aureus adapts to the host nutritional environment by coordinating the activity of central metabolic enzymes

Reginald A. Woods, Iván C. Acosta, Zachary J. Resko, Charles Agbavor, Luka Svet, Manaar Yousef, Wei Ping Teoh, Victor J. Torres, Laty A. Cahoon, Francis Alonzo III

PLOS Pathogens: published May 4, 2026 | https://doi.org/10.1371/journal.ppat.1014183

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1. Correction: Staphylococcus aureus adapts to the host nutritional environment by coordinating the activity of central metabolic enzymes

BnaA07.SUC2 regulated by BnaA05.MYC2 in jasmonate pathway promotes oilseed rape susceptibility to Plasmodiophora brassicae

Jiaqi Liu, Ziyue Xu, Yanlin Li, Shifan Wu, Zihan Ni, Xinmeng Li, Peiyao Li, Xiaoqun Liu, Xinyi Dang, Tianyu Wang, Jingyan Fu, Maolin Wang, Rui Wang

PLOS Pathogens: published May 5, 2026 | https://doi.org/10.1371/journal.ppat.1014199

An orthoflavivirus inhibitor targeting multifunctional NS2A protein, a previously unidentified target

Doortje Borrenberghs, Kitti Wing Ki Chan, Sven Van Brandt, Steffen Jaensch, Milly Ming Ju Choy, Peggy Geluykens, Asmae El Bouayadi, Dax Lauwers, Pradeep Bist, Bart Stoops, Jeroen Van de Ven, Peter Vermeulen, Sarah Megens, Kim Thys, Daniëlle Peeters, Suzanne J. F. Kaptein, Johan Neyts, Subhash G. Vasudevan, Anil Koul, Olivia Goethals

PLOS Pathogens: published May 5, 2026 | https://doi.org/10.1371/journal.ppat.1014190

Immune pathways that regulate neutrophil activation and replenishment prevent persistent pneumococcal colonization

Teniola Idowu, Kristen Lokken-Toyli, Stephen Yeung, Jeffrey N. Weiser

PLOS Pathogens: published May 5, 2026 | https://doi.org/10.1371/journal.ppat.1013899

Coronavirus M protein disperses the trans-Golgi network and inhibits anterograde protein trafficking in the secretory pathway

Taylor M. Caddell, Rory P. Mulloy, Jennifer A. Corcoran, Eric S. Pringle, Craig McCormick

PLOS Pathogens: published May 5, 2026 | https://doi.org/10.1371/journal.ppat.1014117

Globodera pallida virulence on major potato resistance has a common genetic basis across Western Europe

Arno S. Schaveling, Leidy van Rijt, Yoonseon Do, Nike Soffree, Daan Langendoen, Hilde Room, André Machado Bertran, Margien Raven, Sebastiaan P. van Kessel, Evelyn Y.J. van Heese, Stefan J.S. van de Ruitenbeek, Casper C. van Schaik, Sebastian Kiewnick, Geert Smant, Mark G. Sterken

PLOS Pathogens: published May 6, 2026 | https://doi.org/10.1371/journal.ppat.1014201

Human herpesvirus 7 integrates into host telomeres via its telomeric repeat arrays

Yingnan Cheng, Joilson Xavier, Dusan Kunec, Jana Reich, Christiana Victoria Cismaru, Dilan Gün Serdar, Thomas Höfler, Benedikt B. Kaufer

PLOS Pathogens: published May 6, 2026 | https://doi.org/10.1371/journal.ppat.1014189

The stage-specific regulation and role of root-knot nematode SWEET genes

M. Willow H. Maxwell, Bharat Rohilla, Jasper Chippendale, Chris A. Bell

PLOS Pathogens: published May 6, 2026 | https://doi.org/10.1371/journal.ppat.1014161

Wolbachia-induced Cytoplasmic Incompatibility drives epigenetic and maternally-influenced post-embryonic defects

Claire Perez, Jillian Porter, Brandt Warecki, William Sullivan

PLOS Pathogens: published May 7, 2026 | https://doi.org/10.1371/journal.ppat.1014180

Weak selection and stochastic processes limit the emergence of antigenic variants during household transmission of influenza A viruses

Hunter J. Ries, Joseph Lalli, Kelsey R. Florek, Shari Barlow, Maureen Goss, Richard Griesser, Tonya Danz, Amra Uzicanin, Jonathan Temte, Thomas C. Friedrich

PLOS Pathogens: published May 7, 2026 | https://doi.org/10.1371/journal.ppat.1013689

An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen

Bianca M. Coleman, Melissa E. Cook, Md. Robin Khan, Amanda K. Vogel, Anthony J. Wells, Jian Miao, Shachi P. Vyas, Tiffany C. Taylor, Felix E.Y. Aggor, Nicole O. Ponde, Ipsita Dey, Henry Zou, Eldin Jašarević, Brian M. Peters, Sarah L. Gaffen

PLOS Pathogens: published May 7, 2026 | https://doi.org/10.1371/journal.ppat.1014202

SPRY domains encode ubiquitin ligase specificity for ZAP and RIG-I

Ibrahim Syed, Sheng Chen, David J. Peeler, Paul F. McKay, Marco A. Briones-Orta, Jennifer A. Bohn, Robin J. Shattock, Daniel Gonçalves-Carneiro

PLOS Pathogens: published May 8, 2026 | https://doi.org/10.1371/journal.ppat.1014195

A circular RNA vaccine induces durable and cross-protective immunity against Neisseria meningitidis serogroup B in mice

Qiqi Zhang, Dongyu Niu, Yusheng Jia, Lirong Lu, Wenting Wu, Changbin Qu, Zeyun Sun, Shixiong Li, Zhining Liu, Jing Lv, Wentao Wang, Jingyou Yu, Long Zhang, Chuwen Li, Wei Peng, Qingqing Zhang, Shuai Wei

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1013741

Playing both sides – Epstein-Barr Virus accumulates select cellular transcripts to counter virus-mediated host shut-off in lytic cells

Derek Daigle, Ashton Creasy-Marrazzo, Lyn Gradoville, Ayman El-Guindy, Rishabh Mukherjee, Sandeepan Das, Budhadev Baral, Beth A. Rousseau, Richard Park, Michael T. McIntosh, George Miller, Sumita Bhaduri-McIntosh

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014211

Host species-specific mutations in the thumb domain of the 3D^pol polymerase are required for efficient replication of human hepatitis A virus in mice

Ichiro Misumi, Takayoshi Shirasaki, Ling Xie, Bryan Yonish, Olga González-López, Asuka Hirai-Yuki, Xian Chen, You Li, Jason K. Whitmire, Stanley M. Lemon

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014213

A bacterial-type cardiolipin synthase in Plasmodium spp. supports mitochondrial respiration and is important for liver stage maturation

Karavadra Asha Adhur, Nirdosh Nirdosh, Aakash Chandramouli, Swarnali Basu, Amit Lahiri, Siddhesh Shashikant Kamat, Satish Mishra, Saman Habib

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014215

Excessive C5 conversion prevents C9 polymerisation and subsequent MAC-dependent killing of Klebsiella pneumoniae

Kulsum M. Dawoodbhoy, Coco R. Beudeker, Panagiotis Theofilidis, Frerich M. Masson, Michiel van der Flier, Suzan H. M. Rooijakkers, Bart W. Bardoel, Dennis J. Doorduijn

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1013818

Toxoplasma IMC1 is a central component of the subpellicular network and plays critical roles in parasite morphology, replication, and infectivity

Juliette N. Uy, Qing Lou, Z. Hong Zhou, Peter J. Bradley

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014080

Platelet-leucocyte interactions drive MMP-mediated tissue damage in tuberculosis

Daniela E. Kirwan, Deborah L. W. Chong, Oscar Gayoso, Jorge Coronel, Maria-Cristina Loader, Cesar A. Ugarte-Gil, Lilia Cabrera, Ricardo C. Medrano, Kirk A. Taylor, Michael Emerson, Ivan Lozada-Requena, Julia Kutschenreuter, Mirko Zimic, Robert H. Gilman, Jon S. Friedland

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014205

Diversity and evolution of a phase-variable multi-locus antigen in Neisseria gonorrhoeae

QinQin Yu, Tatum D. Mortimer, Sofia O. P. Blomqvist, Bailey Bowcutt, David Helekal, Samantha G. Palace, Yonatan H. Grad

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1013962

Transcriptional factor ATF3 impairs KSHV lytic replication by suppressing the expression of viral bZIP protein K8

Jiazhen Dong, Xiaowei Liang, Yuncai Chen, Jiangwei Peng, Xiaoyi Sun, Jing Huang, Lei Bai, Ke Lan

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014222

Spatiotemporal dynamics of signal dependent exocytosis and parasitophorous vacuolar membrane rupture during Plasmodium falciparum egress

Watcharatip Dedkhad, Tia Tran, Manuel A. Fierro, Carrie Brooks, Vasant Muralidharan

PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014214

Host-specific platelet-activating factor acetylhydrolase selectively remodels diacylglycerophospholipids to control schistosome development

Johanna Ertl, Ulrich Fabien Prodjinotho, Zhigang Rao, Anisuzzaman, Julia Schluckebier, Youssef Hamway, Paula Baar, Haifu Zhao, Martin Haslbeck, Christoph G. Grevelding, Simone Haeberlein, Franco H. Falcone, Sabine Schulz, Andreas Koeberle, Clarissa Prazeres da Costa

PLOS Pathogens: published May 12, 2026 | https://doi.org/10.1371/journal.ppat.1014207

Extensive diversity and impact of drug-resistant HIV-1 variants in individuals with prior virologic failure

Melendhran Pillay, Manish C. Choudhary, Rinki Deo, Serhiy Naumenko, Trevor J. Tamura, Behzad Etemad, Gregory Edelstein, Aabida Khan, Kerusha Govender, Subitha Govender, Philip Tzou, Mary Mick, Zachary T. Herbert, Winnie Muyindike, Mahomed-Yunus Suleman Moosa, Jay Brijkumar, Henry Sunpath, Suzanne McCluskey, Benjamin Chimukangara, Sontaga C. Manyana, Lilishia Gounder, Raveen Parboosing, Kerri-Lee Francois, Robert Shafer, Shannan Ho Sui, Selvan Pillay, Vincent Marconi, Mark J. Siedner, Pravi Moodley, Nokukhanya Msomi, Jonathan Z. Li

PLOS Pathogens: published May 12, 2026 | https://doi.org/10.1371/journal.ppat.1014118

Poliovirus 3D^pol polymerase region is essential for cleavage of poliovirus 3AB in vivo

Minetaro Arita

PLOS Pathogens: published May 13, 2026 | https://doi.org/10.1371/journal.ppat.1014241

Tristetraprolin attenuates schistosomiasis-induced liver fibrosis through m⁶A-mediated regulation of TGF-β1 mRNA stability

Xuejun Zhao, Xinyi Wang, Kejun Liu, Qian Fang, Cheng Wang, Guangbo Mei, Lihua Qu, Jiaxi Zhang, Jiayi Feng, Wenjuan Yang, Junnan Zhu, Hang Zhuo, Na Kuang, Xuebing Qiu, Zhigao Deng, Qiong Luo, Xiaoxia Jin, Lanxuan Jiang, Xiaoqing Li, Huifen Dong, Rui Zhou

PLOS Pathogens: published May 13, 2026 | https://doi.org/10.1371/journal.ppat.1014007

Chemical genetics reveals Leishmania KKT2 and CRK9 kinase activity is required for cell cycle progression

Juliana B. T. Carnielli, James A. Brannigan, Priscila Z. Ramos, Nathaniel G. Jones, Rafael M. Couñago, Peter Sjö, Ana Paula C. A. Lima, Anthony J. Wilkinson, Jeremy C. Mottram

PLOS Pathogens: published May 13, 2026 | https://doi.org/10.1371/journal.ppat.1014194

Collectin-11, a complement pattern recognition molecule, mediates pulmonary SARS-CoV-2 neutralization and protection

Adrian Sutta, Anna Offersgaard, Carlos Rene Duarte Hernandez, Tereza Alica Plchová, Yuyong Zhou, Laura Pérez-Alós, Anne Rosbjerg, Rafael Bayarri-Olmos, Jens Bukh, Beatriz González-García, Judith Margarete Gottwein, Peter Garred

PLOS Pathogens: published May 13, 2026 | https://doi.org/10.1371/journal.ppat.1014216

Leptospiral dissemination is restrained by liver macrophages through Clec4d-driven capture via C/EBPβ activation

Xi Chen, Xin Liu, Jiuxi Liu, Haixin Huang, Wenlong Zhang, Xufeng Xie, Yongguo Cao

PLOS Pathogens: published May 13, 2026 | https://doi.org/10.1371/journal.ppat.1014232

Cryptosporidium secreted proteins form a complex layered interface with the host cell

Annet Puthenpurackal, Sandra Moreno Sanchez, Tifany Schaer, Léna Falconnet, Chengyue Niu, Oscar Vadas, Amandine Guérin

PLOS Pathogens: published May 14, 2026 | https://doi.org/10.1371/journal.ppat.1014212

Characterization of the virus-host RNA-RNA interactome across important human pathogenic RNA viruses

Nkerorema Djodji Damas, Stefan E. Seemann, Rui Costa, Janina Krambrich, Nicolas Fossat, Lizandro R. Rivera-Rangel, Ulrik Fahnøe, Louise Nielsen, Jan Gorodkin, Jens Bukh, Troels K. H. Scheel

PLOS Pathogens: published May 15, 2026 | https://doi.org/10.1371/journal.ppat.1014217

FUT8-mediated core fucosylation of receptor APN drives entry of multiple alphacoronaviruses

Limeng Sun, Yixin Xiang, Yichen Yang, Yubei Tan, Zhelin Su, Zhen Fu, Yanan Fu, Shengsong Xie, Guiqing Peng

PLOS Pathogens: published May 18, 2026 | https://doi.org/10.1371/journal.ppat.1014227

Update and reuse: Structure-guided nanobody evolution against SARS-CoV-2 escape

Fan Bu, Divyasha Saxena, Hailey Turner-Hubbard, Amy Delaney, Lalit Batra, Charlie Fricke, Skyler Moye, Abhishek Verma, Stanley Perlman, Janarjan Bhandari, Bin Liu, Gang Ye, Jian Zheng, Fang Li

PLOS Pathogens: published May 18, 2026 | https://doi.org/10.1371/journal.ppat.1014223

HCMV-pUS2 Disrupts cGAS-STING Signaling through LMAN2L Degradation

Yue-Peng Zhou, Yong-Xuan Yao, Jin-Peng Wu, Yu-Ting Pan, Wen-Bo Zeng, Jin-Yan Sun, Yue Zhao, Han Cheng, Min-Hua Luo, Bo Yang

PLOS Pathogens: published May 18, 2026 | https://doi.org/10.1371/journal.ppat.1014246

The RNA promoter for pathogenic orthoflaviviruses replication is universal and serves as target for viral inhibition

Santiago Oviedo-Rouco, Lautaro Bertoni, Evelyn Mikkelsen, Carolina Sarto, Maria M. Gonzalez Lopez Ledesma, Horacio M. Pallarés, Claudia V. Filomatori, Antonia Bruce, Amanda E. Hargrove, Mehrnoosh Arrar, Andrea V. Gamarnik

PLOS Pathogens: published May 18, 2026 | https://doi.org/10.1371/journal.ppat.1014233

Nuclear transport of human cytomegalovirus tegument protein pp65 through nucleoplasmic reticulum

Maysa Azzeh, Mark F. Santos, Alexandra M. K. Yokomizo, Victoria Cha, Denis Corbeil, Aurelio Lorico

PLOS Pathogens: published May 18, 2026 | https://doi.org/10.1371/journal.ppat.1014224

The carbon starvation-inducible lipoprotein (Slp) influences differential adherence of Escherichia coli O157:H7 at the bovine rectoanal junction

Indira T. Kudva, Erika N. Biernbaum, Eric D. Cassmann, Mitchell V. Palmer, Lekshmi K. Edison, Jessy Castellanos-Gell, Subhashinie Kariyawasam

PLOS Pathogens: published May 18, 2026 | https://doi.org/10.1371/journal.ppat.1013584

Acetylation-mediated regulation of ALV viral proteins: Implications for retroviral inhibition

Ning Cui, Xiaoxia Han, Qinghua Huang, Peipei Wang, Lili Wang, Chuantian Xu, Shuai Su

PLOS Pathogens: published May 18, 2026 | https://doi.org/10.1371/journal.ppat.1014229

β-Klotho inhibited the epithelial-mesenchymal transition of liver sinusoidal endothelial cells to alleviate schistosomiasis liver fibrosis

Tingting Jiang, Qiang Li, Zhihao Yu, Xuanyin Cui, Xiaojin Mo, Quan Chen, Yongruo Chen, Xian Li, Mengyan Wei, Zhaoyu Guo, Yuan Hu, Shizhu Li

PLOS Pathogens: published May 19, 2026 | https://doi.org/10.1371/journal.ppat.1014148

Tripartite motif-containing 34 (TRIM34) protein interacts with the nucleocytoplasmic transport machinery and negatively modulates antiviral responses

Paula Vázquez-Utrilla, Vanessa Rivero, Marta L. DeDiego

PLOS Pathogens: published May 20, 2026 | https://doi.org/10.1371/journal.ppat.1014142

Characterization of a novel cell wall-associated nucleotidase of Enterococcus faecalis that degrades extracellular c-di-AMP

Adriana G. Morales Rivera, Anju Bala, Leila G. Casella, Debra N. Brunson, Ellsa Wongso, Aria Patel, Ilka E. Cuvilly, Alejandro R. Walker, Shannon M. Wallet, Ana L. Flores-Mireles, José A. Lemos

PLOS Pathogens: published May 20, 2026 | https://doi.org/10.1371/journal.ppat.1014206

p1/s1, a 3’-nucleotidase/nuclease, allows Leishmania major to circumvent host innate immune response mechanisms

Stella M. Schmelzle, Michaela Bergmann, Bianca Walber, Jamal Shamsara, Tanja Ziesmann, Ute Distler, Csaba Miskey, Liam Childs, Peter Kolb, Stefan Tenzer, Katrin Bagola, Ger van Zandbergen

PLOS Pathogens: published May 20, 2026 | https://doi.org/10.1371/journal.ppat.1014197

Chemotaxis to plant defense compounds in phytopathogens

Roberta Genova, Ashleigh Holmes, Mario Cano-Muñoz, Atsushi Ishihara, Naoki Ube, Taiji Nomura, Jose A. Gavira, Miguel A. Matilla, Tino Krell

PLOS Pathogens: published May 20, 2026 | https://doi.org/10.1371/journal.ppat.1014240

The hyaluronan receptor CD44 drives COVID-19 severity through its regulation of neutrophil migration

Duncan J. Hart, Md. Jashim Uddin, Rebecca J. Dodd, Savannah G. Brovero, Claire Fleming, Gregory Brett Moreau, Nick R. Natale, Farha Naz, Barbara J. Mann, Tara E. Sutherland, Judith E. Allen, Anthony J. Day, William A. Petri Jr

PLOS Pathogens: published May 20, 2026 | https://doi.org/10.1371/journal.ppat.1013619

Structural basis for sarbecovirus Rc-o319 spike adaptation to Rhinolophus cornutus Bat ACE2 and constraints on switching to human ACE2

Jingjing Wang, Zexuan Li, Yong Ma, Zimu Li, Hang Yuan, Chuanying Niu, Yifeng Teng, Banghui Liu, Mei Li, Min Zhou, Wenxiu Liu, Huimin Feng, Jing Chen, Jun He, Xinwen Chen, Xiaoli Xiong

PLOS Pathogens: published May 21, 2026 | https://doi.org/10.1371/journal.ppat.1014245

Equine infectious anemia virus blocks interferon responses through Rev-mediated activation of the stress granule-PKR-eIF2α pathway

Huiling Ren, Kewei Chen, Bingqian Zhou, Weiguo Zhang, Xue-Feng Wang, Xiaojun Wang

PLOS Pathogens: published May 21, 2026 | https://doi.org/10.1371/journal.ppat.1014262

A murine cytomegalovirus cell cycle regulator (m54.5p) evolved within the conserved viral DNA polymerase gene

Yan Zheng, Ivana Bertovic, Xiangming Han, Thomas Hennig, Adam W. Whisnant, Stephanie Lamer, Andreas Schlosser, Vanda Juranic Lisnic, Penelope Kay-Fedorov, Lars Dölken, Manivel Lodha

PLOS Pathogens: published May 22, 2026 | https://doi.org/10.1371/journal.ppat.1013424

Outer membrane vesicles hijack TIM-1 for cellular uptake

Craig R. MacNair, Varnesh Tiku, Shengya Cao, Ariana D. Sanchez, Barath Udayasuryan, Katharina Theresa Kroll, Adarsh Singh, Man-Wah Tan

PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014256

Partial or complete blocking of gD binding to HVEM affects primary and latent HSV-1 infection as well as eye disease in HSV-1 infected mice

Deepak Arya, Ujjaldeep Jaggi, Jay J. Oh, Shaohui Wang, Homayon Ghiasi

PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014258

Remodeling of tRNA modification in Trypanosoma cruzi life forms

Herbert Guimaraes de Sousa Silva, Janaina de Freitas Nascimento, Marilene Souza Braga, Ana Paula de Jesus Menezes, Ariel M. Silber, Matthew K. Waldor, Julia Pinheiro Chagas da Cunha, Satoshi Kimura

PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014249

PrP turnover in vivo and the time to effect of prion disease therapeutics

Taylor L. Corridon, Jill O’Moore, Alyssa Seerley, Daniel A. Sprague, Yuan Lian, Vanessa Laversenne, Briana Noble, Nikita G. Kamath, Fiona E. Serack, Abdul Basit Shaikh, Brian Erickson, Craig Braun, Kendrick DeSouza-Lenz, Michael Howard, Nathan Chan, Walker S. Jackson, Andrew G. Reidenbach, Deborah E. Cabin, Sonia M. Vallabh, Andrea Grindeland Panter, Nina Oberbeck, Hien T. Zhao, Eric Vallabh Minikel

PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014263

Characterization of inner capsid σA protein as a virulence factor of the pteropine orthoreovirus

Hayato Harima, Michihito Sasaki, Takuma Ariizumi, Nijiho Kawaguchi, Hiroko Kobayashi, Kittiya Intaruck, Takeshi Kobayashi, Takahiro Kawagishi, Yuta Kanai, Naganori Nao, Yongjin Qiu, Masahiro Kajihara, Yasuko Orba, Naoto Ito, Kanako Ishihara, Masayuki Saijo, William W. Hall, Bernard M. Hang’ombe, Hirofumi Sawa

PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014252

Genetic analysis of pyrimidine biosynthetic enzymes in Plasmodium falciparum

Krithika Rajaram, Montana L. Sievert, Rubayet Elahi, James Blauwkamp, Lucas B. Dillard, Sabrina Absalon, Sean T. Prigge

PLOS Pathogens: published May 27, 2026 | https://doi.org/10.1371/journal.ppat.1014269

Modified Anti-PstS1 Bi-specific antibodies unlock potent protection against tuberculosis

Akanksha, Rania Bouzeyen, Avia Watson, Gil Wiseglass, Nyaradzai Sithole, Lilach Abramovitz, Noam Ben-Shalom, Rotem Rubinstein, Babak Javid, Natalia T. Freund

PLOS Pathogens: published May 27, 2026 | https://doi.org/10.1371/journal.ppat.1014133

LuxS/AI-2 regulates phoP/phoQ by a non-canonical mechanism to enhance acid stress survival in Salmonella Typhimurium

Anmol Singh, Abhilash Vijay Nair, Shashanka Aroli, Suman Das, Subhrajit Karmakar, Raju S. Rajmani, Santanu Mukherjee, Umesh Varshney, Dipshikha Chakravortty

PLOS Pathogens: published May 28, 2026 | https://doi.org/10.1371/journal.ppat.1014244

Uridine cytidine kinases govern molnupiravir bioactivation and anti-SARS-CoV-2 activity

Huazhang Shu, Julian M. Ludäscher, Sushma Sharma, Seher Alam, Lilian Frank, Emma Scaletti Hutchinson, Marianna Tampere, Chloé Lévêque, André B.P. van Kuilenburg, Nicholas C.K. Valerie, Mikael Altun, Andrei Chabes, Pål Stenmark, Sean G. Rudd, Si Min Zhang

PLOS Pathogens: published May 29, 2026 | https://doi.org/10.1371/journal.ppat.1014225

Maternal antibody-mediated elimination of a Puumala hantavirus outbreak in a bank vole colony

Stephan Drewes, Julia Wyszkowska, Ewa Jaromin, Joanna Hajduk, Ilona Onik, Mateusz Konczal, Krystyna Lach, Barbara Bober-Sowa, Katarzyna Baliga-Klimczyk, Edyta T. Sadowska, Rainer G. Ulrich, Paweł Koteja

PLOS Pathogens: published May 29, 2026 | https://doi.org/10.1371/journal.ppat.1013693

Correction: Liquid-liquid phase separation mediated immune evasion of respiratory syncytial virus against oligoadenylate synthetase-RNase L pathway

Woo Yeon Hwang, Michael G. Rosenfeld, Soohwan Oh, Young-Chan Kwon

PLOS Pathogens: published May 5, 2026 | https://doi.org/10.1371/journal.ppat.1014193

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Correction: Adaptive morphological changes link to poor clinical outcomes by conferring echinocandin tolerance in Candida tropicalis

Yongqin Wu, Yun Zou, Yuanyuan Dai, Huaiwei Lu, Wei Zhang, Wenjiao Chang, Ying Wang, Zhengchao Nie, Yuanyuan Wang, Xiaohua Jiang

PLOS Pathogens: published May 5, 2026 | https://doi.org/10.1371/journal.ppat.1014188

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Correction: An atypical F-type ATPase is necessary for the function of the antibody cleavage system MIB-MIP in mycoplasmas

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PLOS Pathogens: published May 11, 2026 | https://doi.org/10.1371/journal.ppat.1014203

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Correction: CircRNA ARFGEF1 functions as a ceRNA to promote oncogenic KSHV-encoded viral interferon regulatory factor induction of cell invasion and angiogenesis by upregulating glutaredoxin 3

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PLOS Pathogens: published May 26, 2026 | https://doi.org/10.1371/journal.ppat.1014251

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Homotypic interactions between SLAMF1 receptors on innate T cells and neutrophils regulate killing of fungi

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