Viral endosymbiotic infection of protozoan parasites: How it influences the development of cutaneous leishmaniasis

Andrea Lafleur, Martin Olivier

PLOS Pathogens: published November 3, 2022 | https://doi.org/10.1371/journal.ppat.1010910

Dissecting the mechanisms of pathogenesis in cerebral malaria

Arathy Ramachandran, Amit Sharma

PLOS Pathogens: published November 17, 2022 | https://doi.org/10.1371/journal.ppat.1010919

Infectious origin of Alzheimer’s disease: Amyloid beta as a component of brain antimicrobial immunity

Iveta Vojtechova, Tomas Machacek, Zdenka Kristofikova, Ales Stuchlik, Tomas Petrasek

PLOS Pathogens: published November 17, 2022 | https://doi.org/10.1371/journal.ppat.1010929

A VPS15-like kinase regulates apicoplast biogenesis and autophagy by promoting PI3P generation in Toxoplasma gondii

Rahul Singh Rawat, Priyanka Bansal, Pushkar Sharma

PLOS Pathogens: published November 1, 2022 | https://doi.org/10.1371/journal.ppat.1010922

RNase L activation in the cytoplasm induces aberrant processing of mRNAs in the nucleus

James M. Burke, Nina Ripin, Max B. Ferretti, Laura A. St Clair, Emma R. Worden-Sapper, Fernando Salgado, Sara L. Sawyer, Rushika Perera, Kristen W. Lynch, Roy Parker

PLOS Pathogens: published November 1, 2022 | https://doi.org/10.1371/journal.ppat.1010930

NF kappa B regulator Bcl3 controls development and function of classical dendritic cells required for resistance to Toxoplasma gondii

June Guha, Byunghyun Kang, Estefania Claudio, Neelam R. Redekar, Hongshan Wang, Brian L. Kelsall, Ulrich Siebenlist, Philip M. Murphy

PLOS Pathogens: published November 1, 2022 | https://doi.org/10.1371/journal.ppat.1010502

Unique cellular immune signatures of multisystem inflammatory syndrome in children

Anuradha Rajamanickam, Pavan Kumar Nathella, Aishwarya Venkataraman, Poovazhagi Varadarjan, Srinithi Kannan, Arul Nancy Pandiarajan, Rachel Mariam Renji, Elayarani Elavarasan, Akshith Thimmaiah, Kandasamy Sasidaran, Nedunchelian Krishnamoorthy, Suresh Natarajan, Ganesh Ramaswamy, Balasubramanian Sundaram, Sulochana Putlibai, Syed Hissar, Elilarasi Selladurai, K. Ranganathan Uma Devi, Thomas B. Nutman, Subash Babu

PLOS Pathogens: published November 2, 2022 | https://doi.org/10.1371/journal.ppat.1010915

Polar localization of CheO under hypoxia promotes Campylobacter jejuni chemotactic behavior within host

Ran Mo, Wenhui Ma, Weijie Zhou, Beile Gao

PLOS Pathogens: published November 3, 2022 | https://doi.org/10.1371/journal.ppat.1010953

HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy

Aniqa Shahid, Bradley R. Jones, Julia S. W. Yang, Winnie Dong, Tawimas Shaipanich, Kathryn Donohoe, Chanson J. Brumme, Jeffrey B. Joy, Janice M. Leung, Zabrina L. Brumme

PLOS Pathogens: published November 4, 2022 | https://doi.org/10.1371/journal.ppat.1010613

Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

Forrest Hoyt, Parvez Alam, Efrosini Artikis, Cindi L. Schwartz, Andrew G. Hughson, Brent Race, Chase Baune, Gregory J. Raymond, Gerald S. Baron, Allison Kraus, Byron Caughey

PLOS Pathogens: published November 7, 2022 | https://doi.org/10.1371/journal.ppat.1010947

Cross-protection against African swine fever virus upon intranasal vaccination is associated with an adaptive-innate immune crosstalk

Laia Bosch-Camós, Uxía Alonso, Anna Esteve-Codina, Chia-Yu Chang, Beatriz Martín-Mur, Francesc Accensi, Marta Muñoz, María J. Navas, Marc Dabad, Enric Vidal, Sonia Pina-Pedrero, Patricia Pleguezuelos, Ginevra Caratù, María L. Salas, Lihong Liu, Stanimira Bataklieva, Boris Gavrilov, Fernando Rodríguez, Jordi Argilaguet

PLOS Pathogens: published November 9, 2022 | https://doi.org/10.1371/journal.ppat.1010931

Aspergillus fumigatus Elongator complex subunit 3 affects hyphal growth, adhesion and virulence through wobble uridine tRNA modification

Yuanwei Zhang, Yamei Wang, Jialu Fan, Guoxing Zhu, Ling Lu

PLOS Pathogens: published November 14, 2022 | https://doi.org/10.1371/journal.ppat.1010976

Antibiotic tolerance and persistence have distinct fitness trade-offs

Charlotte Michaux, Séverin Ronneau, Rachel T. Giorgio, Sophie Helaine

PLOS Pathogens: published November 14, 2022 | https://doi.org/10.1371/journal.ppat.1010963

A Caenorhabditis elegans nck-1 and filamentous actin-regulating protein pathway mediates a key cellular defense against bacterial pore-forming proteins

Anand Sitaram, Yunqiang Yin, Tammy Zamaitis, Bo Zhang, Raffi V. Aroian

PLOS Pathogens: published November 14, 2022 | https://doi.org/10.1371/journal.ppat.1010656

The herpes simplex virus tegument protein pUL21 is required for viral genome retention within capsids

Ethan C. M. Thomas, Maike Bossert, Bruce W. Banfield

PLOS Pathogens: published November 14, 2022 | https://doi.org/10.1371/journal.ppat.1010969

Mitochondrial ROS production by neutrophils is required for host antimicrobial function against Streptococcus pneumoniae and is controlled by A2B adenosine receptor signaling

Sydney E. Herring, Sovathiro Mao, Manmeet Bhalla, Essi Y. I. Tchalla, Jill M. Kramer, Elsa N. Bou Ghanem

PLOS Pathogens: published November 14, 2022 | https://doi.org/10.1371/journal.ppat.1010700

Reconstitution of an N-AChR from Brugia malayi, an evolved change in acetylcholine receptor accessory protein requirements in filarial parasites

Jennifer D. Noonan, Robin N. Beech

PLOS Pathogens: published November 14, 2022 | https://doi.org/10.1371/journal.ppat.1010962

Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects

Sabrina Mazouz, Eduardo Salinas, Nathalie Bédard, Ali Filali, Omar Khedr, Leo Swadling, Mohamed S. Abdel-Hakeem, Asiyah Siddique, Eleanor Barnes, Julie Bruneau, Arash Grakoui, Naglaa H. Shoukry

PLOS Pathogens: published November 15, 2022 | https://doi.org/10.1371/journal.ppat.1010968

Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA

Sai Sundar Rajan Raghavan, Robert Dagil, Mary Lopez-Perez, Julian Conrad, Maria Rosaria Bassi, Maria del Pilar Quintana, Swati Choudhary, Tobias Gustavsson, Yong Wang, Pontus Gourdon, Michael Fokuo Ofori, Sebastian Boje Christensen, Daniel Thomas Remias Minja, Christentze Schmiegelow, Morten Agertoug Nielsen, Lea Barfod, Lars Hviid, Ali Salanti, Thomas Lavstsen, Kaituo Wang

PLOS Pathogens: published November 16, 2022 | https://doi.org/10.1371/journal.ppat.1010924

Midgut membrane protein BmSUH facilitates Bombyx mori nucleopolyhedrovirus oral infection

Yanting Liang, Weifan Xu, Yanyan Zhou, Yun Gao, Huan Tian, Xiaofeng Wu, Yusong Xu, Huabing Wang

PLOS Pathogens: published November 16, 2022 | https://doi.org/10.1371/journal.ppat.1010938

Dissection of Besnoitia besnoiti intermediate host life cycle stages: From morphology to gene expression

Chandra Ramakrishnan, Aarti Krishnan, Samuel Francisco, Marc W. Schmid, Giancarlo Russo, Alexandre Leitão, Andrew Hemphill, Dominique Soldati-Favre, Adrian B. Hehl

PLOS Pathogens: published November 17, 2022 | https://doi.org/10.1371/journal.ppat.1010955

Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer

Jelle van Schooten, Anna Schorcht, Elinaz Farokhi, Jeffrey C. Umotoy, Hongmei Gao, Tom L. G. M. van den Kerkhof, Jessica Dorning, Tim G. Rijkhold Meesters, Patricia van der Woude, Judith A. Burger, Tom Bijl, Riham Ghalaiyini, Alba Torrents de la Peña, Hannah L. Turner, Celia C. Labranche, Robyn L. Stanfield, Devin Sok, Hanneke Schuitemaker, David C. Montefiori, Dennis R. Burton, Gabriel Ozorowski, Michael S. Seaman, Ian A. Wilson, Rogier W. Sanders, Andrew B. Ward, Marit J. van Gils

PLOS Pathogens: published November 17, 2022 | https://doi.org/10.1371/journal.ppat.1010945

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Tyler N. Starr, Allison J. Greaney, Cameron M. Stewart, Alexandra C. Walls, William W. Hannon, David Veesler, Jesse D. Bloom

PLOS Pathogens: published November 18, 2022 | https://doi.org/10.1371/journal.ppat.1010951

Dissecting the invasion of Galleria mellonella by Yersinia enterocolitica reveals metabolic adaptations and a role of a phage lysis cassette in insect killing

Philipp-Albert Sänger, Stefanie Wagner, Elisabeth M. Liebler-Tenorio, Thilo M. Fuchs

PLOS Pathogens: published November 18, 2022 | https://doi.org/10.1371/journal.ppat.1010991

The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness

Elena Sugrue, Arthur Wickenhagen, Nardus Mollentze, Muhamad Afiq Aziz, Vattipally B. Sreenu, Sven Truxa, Lily Tong, Ana da Silva Filipe, David L. Robertson, Joseph Hughes, Suzannah J. Rihn, Sam J. Wilson

PLOS Pathogens: published November 18, 2022 | https://doi.org/10.1371/journal.ppat.1010973

Paeniclostridium sordellii uterine infection is dependent on the estrous cycle

Sarah C. Bernard, M. Kay Washington, D. Borden Lacy

PLOS Pathogens: published November 21, 2022 | https://doi.org/10.1371/journal.ppat.1010997

Mitochondrial protein, TBRG4, modulates KSHV and EBV reactivation from latency

Huirong Zhang, Jason P. Wong, Guoxin Ni, Patricio Cano, Dirk P. Dittmer, Blossom Damania

PLOS Pathogens: published November 23, 2022 | https://doi.org/10.1371/journal.ppat.1010990

Small immune effectors coordinate peptidoglycan-derived immunity to regulate intestinal bacteria in shrimp

Ping-Ping Liu, Zhe Wei, Zi-Hua Cheng, Xian-Wei Wang

PLOS Pathogens: published November 23, 2022 | https://doi.org/10.1371/journal.ppat.1010967

Genomic changes in Kaposi Sarcoma-associated Herpesvirus and their clinical correlates

Jan Clement Santiago, Scott V. Adams, Andrea Towlerton, Fred Okuku, Warren Phipps, James I. Mullins

PLOS Pathogens: published November 28, 2022 | https://doi.org/10.1371/journal.ppat.1010524

The DEAD-box RNA helicase Dhx15 controls glycolysis and arbovirus replication in Aedes aegypti mosquito cells

Samara Rosendo Machado, Jieqiong Qu, Werner J. H. Koopman, Pascal Miesen

PLOS Pathogens: published November 28, 2022 | https://doi.org/10.1371/journal.ppat.1010694

High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire

Iga Kucharska, Špela Binter, Rajagopal Murugan, Stephen W. Scally, Julia Ludwig, Katherine Prieto, Elaine Thai, Giulia Costa, Kan Li, Gillian Q. Horn, Yevel Flores-Garcia, Alexandre Bosch, Taylor Sicard, John L. Rubinstein, Fidel Zavala, S. Moses Dennison, Georgia D. Tomaras, Elena A. Levashina, Paul Kellam, Hedda Wardemann, Jean-Philippe Julien

PLOS Pathogens: published November 28, 2022 | https://doi.org/10.1371/journal.ppat.1010999

Dynamics and consequences of the HTLV-1 proviral plus-strand burst

Saumya Ramanayake, Dale A. Moulding, Yuetsu Tanaka, Abhyudai Singh, Charles R. M. Bangham

PLOS Pathogens: published November 28, 2022 | https://doi.org/10.1371/journal.ppat.1010774

MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST

Yi Tu, Xiu-Juan Yin, Qian Liu, Shan Zhang, Jie Wang, Ben-Zhe Ji, Jie Zhang, Ming-Shun Sun, Yang Yang, Chen-Hui Wang, Lei Yin, Yu Liu

PLOS Pathogens: published November 30, 2022 | https://doi.org/10.1371/journal.ppat.1010989

The Streptococcus pyogenes hyaluronic acid capsule promotes experimental nasal and skin infection by preventing neutrophil-mediated clearance

Jacklyn R. Hurst, Blake A. Shannon, Heather C. Craig, Aanchal Rishi, Stephen W. Tuffs, John K. McCormick

PLOS Pathogens: published November 30, 2022 | https://doi.org/10.1371/journal.ppat.1011013

Two apicoplast dwelling glycolytic enzymes provide key substrates for metabolic pathways in the apicoplast and are critical for Toxoplasma growth

Zhipeng Niu, Shu Ye, Jiaojiao Liu, Mengyu Lyu, Lilan Xue, Muxiao Li, Congcong Lyu, Junlong Zhao, Bang Shen

PLOS Pathogens: published November 30, 2022 | https://doi.org/10.1371/journal.ppat.1011009

Correction: Maintenance of divergent lineages of the Rice Blast Fungus Pyricularia oryzae through niche separation, loss of sex and post-mating genetic incompatibilities

Maud Thierry, Florian Charriat, Joëlle Milazzo, Henri Adreit, Sébastien Ravel, Sandrine Cros-Arteil, Sonia borron, Violaine Sella, Thomas Kroj, Renaud Ioos, Elisabeth Fournier, Didier Tharreau, Pierre Gladieux

PLOS Pathogens: published November 7, 2022 | https://doi.org/10.1371/journal.ppat.1010944

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Correction: India can consider integration of three eliminable disease control programmes on malaria, lymphatic filariasis, and visceral leishmaniasis

Manju Rahi, Rini Chaturvedi, Payal Das, Amit Sharma

PLOS Pathogens: published November 21, 2022 | https://doi.org/10.1371/journal.ppat.1010984

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Correction: Exploring links between vitamin D deficiency and COVID-19

Mradul Mohan, Jerin Jose Cherian, Amit Sharma

PLOS Pathogens: published November 21, 2022 | https://doi.org/10.1371/journal.ppat.1010985

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Correction: Current status of therapeutic monoclonal antibodies against SARS-CoV-2

Sanjeev Kumar, Anmol Chandele, Amit Sharma

PLOS Pathogens: published November 21, 2022 | https://doi.org/10.1371/journal.ppat.1010983

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Correction: The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation

Tiziana Ginex, Clara Marco-Marín, Miłosz Wieczór, Carlos P. Mata, James Krieger, Paula Ruiz-Rodriguez, Maria Luisa López-Redondo, Clara Francés-Gómez, Roberto Melero, Carlos Óscar Sánchez-Sorzano, Marta Martínez, Nadine Gougeard, Alicia Forcada-Nadal, Sara Zamora-Caballero, Roberto Gozalbo-Rovira, Carla Sanz-Frasquet, Rocío Arranz, Jeronimo Bravo, Vicente Rubio, Alberto Marina, The IBV-Covid19-Pipeline, Ron Geller, Iñaki Comas, Carmen Gil, Mireia Coscolla, Modesto Orozco, José Luis Llácer, Jose-Maria Carazo

PLOS Pathogens: published November 23, 2022 | https://doi.org/10.1371/journal.ppat.1010995

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Correction: A new adenine nucleotide transporter located in the ER is essential for maintaining the growth of Toxoplasma gondii

Senyang Li, Jiahui Qian, Ming Xu, Jing Yang, Zhengming He, Tongjie Zhao, Junlong Zhao, Rui Fang

PLOS Pathogens: published November 29, 2022 | https://doi.org/10.1371/journal.ppat.1010998

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Correction: An in vitro method for inducing titan cells reveals novel features of yeast-to-titan switching in the human fungal pathogen Cryptococcus gattii

Lamin Saidykhan, Joao Correia, Andrey Romanyuk, Anna F. A. Peacock, Guillaume E. Desanti, Leanne Taylor-Smith, Maria Makarova, Elizabeth R. Ballou, Robin C. May

PLOS Pathogens: published November 29, 2022 | https://doi.org/10.1371/journal.ppat.1011001

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Correction: A vesicular stomatitis virus-based prime-boost vaccination strategy induces potent and protective neutralizing antibodies against SARS-CoV-2

Gyoung Nyoun Kim, Jung-ah Choi, Kunyu Wu, Nasrin Saeedian, Eunji Yang, Hayan Park, Sun-Je Woo, Gippeum Lim, Seong-Gyu Kim, Su-Kyeong Eo, Hoe Won Jeong, Taewoo Kim, Jae-Hyung Chang, Sang Hwan Seo, Na Hyung Kim, Eunsil Choi, Seungho Choo, Sangkyun Lee, Andrew Winterborn, Yue Li, Kate Parham, Justin M. Donovan, Brock Fenton, Jimmy D. Dikeakos, Gregory A. Dekaban, S. M. Mansour Haeryfar, Ryan M. Troyer, Eric J. Arts, Stephen D. Barr, Manki Song, C. Yong Kang

PLOS Pathogens: published November 29, 2022 | https://doi.org/10.1371/journal.ppat.1011000

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Correction: Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection

Aaqib Sohail, Azeem A. Iqbal, Nishika Sahini, Fangfang Chen, Mohamed Tantawy, Syed F. H. Waqas, Moritz Winterhoff, Thomas Ebensen, Kristin Schultz, Robert Geffers, Klaus Schughart, Matthias Preusse, Mahmoud Shehata, Heike Bähre, Marina C. Pils, Carlos A. Guzman, Ahmed Mostafa, Stephan Pleschka, Christine Falk, Alessandro Michelucci, Frank Pessler

PLOS Pathogens: published November 29, 2022 | https://doi.org/10.1371/journal.ppat.1011002

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