Each row of the figure shows several cells of a different trypanosome species or strain. Characteristic cellular waveforms are identifiable with the three-dimensional views of single cells. Additionally, the variation between individual snapshots can be visualised. Trypanosomes are incessant swimmers and thus, there is no resting morphology that can be described. In fact, the product of physical parameters of the cell, the swimming capacity and the microenvironment give the parasites their characteristic appearance, here termed the cellular waveform, which could explain species-specific dissemination and annidation in the mammalian host (see Engstler et al., Fig. 5).
Image Credit: Engstler et al.
Viewpoints
PLOS Pathogens 2015 Reviewer Thank You
PLOS Pathogens: published February 23, 2016 | https://doi.org/10.1371/journal.ppat.1005497
Pearls
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