April 2014

The burst of a measles virus induced syncytium of 6 six cells is captured by confocal fluorescence microscopy. See Runge et al.

Image Credit: Konstantin M. J. Sparrer, Max von Pettenkofer-Institute, Gene Center, Ludwig-Maximilians University Munich

Opinions

Cryptosporidium, Giardia, Cryptococcus, Pneumocystis Genetic Variability: Cryptic Biological Species or Clonal Near-Clades?

Michel Tibayrenc, Francisco J. Ayala

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1003908

Early Mortality Syndrome Outbreaks: A Microbial Management Issue in Shrimp Farming?

Peter De Schryver, Tom Defoirdt, Patrick Sorgeloos

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1003919

Pearls

Candida Vaginitis: When Opportunism Knocks, the Host Responds

Brian M. Peters, Junko Yano, Mairi C. Noverr, Paul L. Fidel Jr

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1003965

The 2010 Cholera Outbreak in Haiti: How Science Solved a Controversy

Fabini D. Orata, Paul S. Keim, Yan Boucher

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1003967

Pernicious Pathogens or Expedient Elements of Inheritance: The Significance of Yeast Prions

James S. Byers, Daniel F. Jarosz

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1003992

The HMW1C-Like Glycosyltransferases—An Enzyme Family with a Sweet Tooth for Simple Sugars

Jessica R. McCann, Joseph W. St. Geme III

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1003977

Plastic Proteins and Monkey Blocks: How Lentiviruses Evolved to Replicate in the Presence of Primate Restriction Factors

Kevin R. McCarthy, Welkin E. Johnson

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004017

Wormholes in Host Defense: How Helminths Manipulate Host Tissues to Survive and Reproduce

Deborah Boyett, Michael H. Hsieh

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004014

An Overview of Respiratory Syncytial Virus

Jia Meng, Christopher C. Stobart, Anne L. Hotard, Martin L. Moore

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004016

Mining Herbaria for Plant Pathogen Genomes: Back to the Future

Kentaro Yoshida, Hernán A. Burbano, Johannes Krause, Marco Thines, Detlef Weigel, Sophien Kamoun

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004028

Research Articles

Microbial Pathogens Trigger Host DNA Double-Strand Breaks Whose Abundance Is Reduced by Plant Defense Responses

Junqi Song, Andrew F. Bent

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004030

First Experimental In Vivo Model of Enhanced Dengue Disease Severity through Maternally Acquired Heterotypic Dengue Antibodies

Jowin Kai Wei Ng, Summer Lixin Zhang, Hwee Cheng Tan, Benedict Yan, Julia Maria Martinez Gomez, Wei Yu Tan, Jian Hang Lam, Grace Kai Xin Tan, Eng Eong Ooi, Sylvie Alonso

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004031

Regulation of Human T-Lymphotropic Virus Type I Latency and Reactivation by HBZ and Rex

Subha Philip, Muhammad Atif Zahoor, Huijun Zhi, Yik-Khuan Ho, Chou-Zen Giam

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004040

A Human Lung Xenograft Mouse Model of Nipah Virus Infection

Gustavo Valbuena, Hailey Halliday, Viktoriya Borisevich, Yenny Goez, Barry Rockx

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004063

Efficient Parvovirus Replication Requires CRL4^Cdt2-Targeted Depletion of p21 to Prevent Its Inhibitory Interaction with PCNA

Richard O. Adeyemi, Matthew S. Fuller, David J. Pintel

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004055

The Pathogenic Mechanism of the Mycobacterium ulcerans Virulence Factor, Mycolactone, Depends on Blockade of Protein Translocation into the ER

Belinda S. Hall, Kirsti Hill, Michael McKenna, Joy Ogbechi, Stephen High, Anne E. Willis, Rachel E. Simmonds

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004061

A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage

Pierre Cavailles, Pierre Flori, Olivier Papapietro, Cordelia Bisanz, Dominique Lagrange, Ludovic Pilloux, Céline Massera, Sara Cristinelli, Delphine Jublot, Olivier Bastien, Corinne Loeuillet, Delphine Aldebert, Bastien Touquet, Gilbert J. Fournié, Marie France Cesbron-Delauw

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004005

Progressive Accumulation of Activated ERK2 within Highly Stable ORF45-Containing Nuclear Complexes Promotes Lytic Gammaherpesvirus Infection

Evonne N. Woodson, Melissa S. Anderson, Matthew S. Loftus, Dean H. Kedes

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004066

Caspase-1-Like Regulation of the proPO-System and Role of ppA and Caspase-1-Like Cleaved Peptides from proPO in Innate Immunity

Miti Jearaphunt, Chadanat Noonin, Pikul Jiravanichpaisal, Seiko Nakamura, Anchalee Tassanakajon, Irene Söderhäll, Kenneth Söderhäll

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004059

A Neutralizing Anti-gH/gL Monoclonal Antibody Is Protective in the Guinea Pig Model of Congenital CMV Infection

Marcy R. Auerbach, Donghong Yan, Rajesh Vij, Jo-Anne Hongo, Gerald Nakamura, Jean-Michel Vernes, Y. Gloria Meng, Samantha Lein, Pamela Chan, Jed Ross, Richard Carano, Rong Deng, Nicholas Lewin-Koh, Min Xu, Becket Feierbach

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004060

Parasite Fate and Involvement of Infected Cells in the Induction of CD4⁺ and CD8⁺ T Cell Responses to Toxoplasma gondii

Christopher D. Dupont, David A. Christian, Elizabeth M. Selleck, Marion Pepper, Michael Leney-Greene, Gretchen Harms Pritchard, Anita A. Koshy, Sagie Wagage, Morgan A. Reuter, L. David Sibley, Michael R. Betts, Christopher A. Hunter

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004047

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

Christoph Schneider, Samuel P. Nobs, Alex K. Heer, Michael Kurrer, Glynis Klinke, Nico van Rooijen, Johannes Vogel, Manfred Kopf

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004053

Inferring Influenza Infection Attack Rate from Seroprevalence Data

Joseph T. Wu, Kathy Leung, Ranawaka A. P. M. Perera, Daniel K. W. Chu, Cheuk Kwong Lee, Ivan F. N. Hung, Che Kit Lin, Su-Vui Lo, Yu-Lung Lau, Gabriel M. Leung, Benjamin J. Cowling, J. S. Malik Peiris

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004054

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

Jeanette Wagener, R. K. Subbarao Malireddi, Megan D. Lenardon, Martin Köberle, Simon Vautier, Donna M. MacCallum, Tilo Biedermann, Martin Schaller, Mihai G. Netea, Thirumala-Devi Kanneganti, Gordon D. Brown, Alistair J. P. Brown, Neil A. R. Gow

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004050

pelo Is Required for High Efficiency Viral Replication

Xiurong Wu, Wan-Ting He, Shuye Tian, Dan Meng, Yuanyue Li, Wanze Chen, Lisheng Li, Lili Tian, Chuan-Qi Zhong, Felicia Han, Jianming Chen, Jiahuai Han

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004034

Evidence That Bank Vole PrP Is a Universal Acceptor for Prions

Joel C. Watts, Kurt Giles, Smita Patel, Abby Oehler, Stephen J. DeArmond, Stanley B. Prusiner

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1003990

Complement-Related Proteins Control the Flavivirus Infection of Aedes aegypti by Inducing Antimicrobial Peptides

Xiaoping Xiao, Yang Liu, Xiaoyan Zhang, Jing Wang, Zuofeng Li, Xiaojing Pang, Penghua Wang, Gong Cheng

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004027

IFITM3 Restricts Influenza A Virus Entry by Blocking the Formation of Fusion Pores following Virus-Endosome Hemifusion

Tanay M. Desai, Mariana Marin, Christopher R. Chin, George Savidis, Abraham L. Brass, Gregory B. Melikyan

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004048

A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity

Hangfei Qi, C. Anders Olson, Nicholas C. Wu, Ruian Ke, Claude Loverdo, Virginia Chu, Shawna Truong, Roland Remenyi, Zugen Chen, Yushen Du, Sheng-Yao Su, Laith Q. Al-Mawsawi, Ting-Ting Wu, Shu-Hua Chen, Chung-Yen Lin, Weidong Zhong, James O. Lloyd-Smith, Ren Sun

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004064

Coxsackievirus-Induced miR-21 Disrupts Cardiomyocyte Interactions via the Downregulation of Intercalated Disk Components

Xin Ye, Huifang Mary Zhang, Ye Qiu, Paul J. Hanson, Maged Gomaa Hemida, Wei Wei, Pamela A. Hoodless, Fanny Chu, Decheng Yang

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004070

Host-to-Pathogen Gene Transfer Facilitated Infection of Insects by a Pathogenic Fungus

Hong Zhao, Chuan Xu, Hsiao-Ling Lu, Xiaoxuan Chen, Raymond J. St. Leger, Weiguo Fang

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004009

Estimating the Fitness Advantage Conferred by Permissive Neuraminidase Mutations in Recent Oseltamivir-Resistant A(H1N1)pdm09 Influenza Viruses

Jeff Butler, Kathryn A. Hooper, Stephen Petrie, Raphael Lee, Sebastian Maurer-Stroh, Lucia Reh, Teagan Guarnaccia, Chantal Baas, Lumin Xue, Sophie Vitesnik, Sook-Kwan Leang, Jodie McVernon, Anne Kelso, Ian G. Barr, James M. McCaw, Jesse D. Bloom, Aeron C. Hurt

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004065

Inactivation of Genes for Antigenic Variation in the Relapsing Fever Spirochete Borrelia hermsii Reduces Infectivity in Mice and Transmission by Ticks

Sandra J. Raffel, James M. Battisti, Robert J. Fischer, Tom G. Schwan

PLOS Pathogens: published April 3, 2014 | https://doi.org/10.1371/journal.ppat.1004056

Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing

Datsen George Wei, Vicki Chiang, Elizabeth Fyne, Mini Balakrishnan, Tiffany Barnes, Michael Graupe, Joseph Hesselgesser, Alivelu Irrinki, Jeffrey P. Murry, George Stepan, Kirsten M. Stray, Angela Tsai, Helen Yu, Jonathan Spindler, Mary Kearney, Celsa A. Spina, Deborah McMahon, Jacob Lalezari, Derek Sloan, John Mellors, Romas Geleziunas, Tomas Cihlar

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004071

Coxsackievirus B Exits the Host Cell in Shed Microvesicles Displaying Autophagosomal Markers

Scott M. Robinson, Ginger Tsueng, Jon Sin, Vrushali Mangale, Shahad Rahawi, Laura L. McIntyre, Wesley Williams, Nelson Kha, Casey Cruz, Bryan M. Hancock, David P. Nguyen, M. Richard Sayen, Brett J. Hilton, Kelly S. Doran, Anca M. Segall, Roland Wolkowicz, Christopher T. Cornell, J. Lindsay Whitton, Roberta A. Gottlieb, Ralph Feuer

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004045

Cytosolic Peroxidases Protect the Lysosome of Bloodstream African Trypanosomes from Iron-Mediated Membrane Damage

Corinna Hiller, Amrei Nissen, Diego Benítez, Marcelo A. Comini, R. Luise Krauth-Siegel

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004075

In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells

Simon Runge, Konstantin M. J. Sparrer, Charlotte Lässig, Katharina Hembach, Alina Baum, Adolfo García-Sastre, Johannes Söding, Karl-Klaus Conzelmann, Karl-Peter Hopfner

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004081

Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway

Peihong Dai, Weiyi Wang, Hua Cao, Francesca Avogadri, Lianpan Dai, Ingo Drexler, Johanna A. Joyce, Xiao-Dong Li, Zhijian Chen, Taha Merghoub, Stewart Shuman, Liang Deng

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1003989

Potent Dengue Virus Neutralization by a Therapeutic Antibody with Low Monovalent Affinity Requires Bivalent Engagement

Melissa A. Edeling, S. Kyle Austin, Bimmi Shrestha, Kimberly A. Dowd, Swati Mukherjee, Christopher A. Nelson, Syd Johnson, Manu N. Mabila, Elizabeth A. Christian, Joseph Rucker, Theodore C. Pierson, Michael S. Diamond, Daved H. Fremont

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004072

The Expanding Functions of Cellular Helicases: The Tombusvirus RNA Replication Enhancer Co-opts the Plant eIF4AIII-Like AtRH2 and the DDX5-Like AtRH5 DEAD-Box RNA Helicases to Promote Viral Asymmetric RNA Replication

Nikolay Kovalev, Peter D. Nagy

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004051

Affinity Proteomics Reveals Elevated Muscle Proteins in Plasma of Children with Cerebral Malaria

Julie Bachmann, Florence Burté, Setia Pramana, Ianina Conte, Biobele J. Brown, Adebola E. Orimadegun, Wasiu A. Ajetunmobi, Nathaniel K. Afolabi, Francis Akinkunmi, Samuel Omokhodion, Felix O. Akinbami, Wuraola A. Shokunbi, Caroline Kampf, Yudi Pawitan, Mathias Uhlén, Olugbemiro Sodeinde, Jochen M. Schwenk, Mats Wahlgren, Delmiro Fernandez-Reyes, Peter Nilsson

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004038

An Interaction between Glutathione and the Capsid Is Required for the Morphogenesis of C-Cluster Enteroviruses

Hsin-Chieh Ma, Ying Liu, Chunling Wang, Michael Strauss, Nina Rehage, Ying-Han Chen, Nihal Altan-Bonnet, James Hogle, Eckard Wimmer, Steffen Mueller, Aniko V. Paul, Ping Jiang

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004052

Deficient IFN Signaling by Myeloid Cells Leads to MAVS-Dependent Virus-Induced Sepsis

Amelia K. Pinto, Hilario J. Ramos, Xiaobo Wu, Shilpa Aggarwal, Bimmi Shrestha, Matthew Gorman, Kristin Y. Kim, Mehul S. Suthar, John P. Atkinson, Michael Gale Jr, Michael S. Diamond

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004086

Binding of Glutathione to Enterovirus Capsids Is Essential for Virion Morphogenesis

Hendrik Jan Thibaut, Lonneke van der Linden, Ping Jiang, Bert Thys, María-Dolores Canela, Leire Aguado, Bart Rombaut, Eckard Wimmer, Aniko Paul, María-Jesús Pérez-Pérez, Frank J. M. van Kuppeveld, Johan Neyts

PLOS Pathogens: published April 10, 2014 | https://doi.org/10.1371/journal.ppat.1004039

TCR Affinity Associated with Functional Differences between Dominant and Subdominant SIV Epitope-Specific CD8⁺ T Cells in Mamu-A01*⁺ Rhesus Monkeys

Christa E. Osuna, Ana Maria Gonzalez, Hsun-Hsien Chang, Amy Shi Hung, Elizabeth Ehlinger, Kara Anasti, S. Munir Alam, Norman L. Letvin

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004069

Kind Discrimination and Competitive Exclusion Mediated by Contact-Dependent Growth Inhibition Systems Shape Biofilm Community Structure

Melissa S. Anderson, Erin C. Garcia, Peggy A. Cotter

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004076

Structural Differences Explain Diverse Functions of Plasmodium Actins

Juha Vahokoski, Saligram Prabhakar Bhargav, Ambroise Desfosses, Maria Andreadaki, Esa-Pekka Kumpula, Silvia Muñico Martinez, Alexander Ignatev, Simone Lepper, Friedrich Frischknecht, Inga Sidén-Kiamos, Carsten Sachse, Inari Kursula

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004091

Exposure-Dependent Control of Malaria-Induced Inflammation in Children

Silvia Portugal, Jacqueline Moebius, Jeff Skinner, Safiatou Doumbo, Didier Doumtabe, Younoussou Kone, Seydou Dia, Kishore Kanakabandi, Daniel E. Sturdevant, Kimmo Virtaneva, Stephen F. Porcella, Shanping Li, Ogobara K. Doumbo, Kassoum Kayentao, Aissata Ongoiba, Boubacar Traore, Peter D. Crompton

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004079

Role of Calmodulin-Calmodulin Kinase II, cAMP/Protein Kinase A and ERK 1/2 on Aeromonas hydrophila-Induced Apoptosis of Head Kidney Macrophages

Chaitali Banerjee, Preeti Khatri, Rajagopal Raman, Himanshi Bhatia, Malabika Datta, Shibnath Mazumder

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004018

The Apical Complex Provides a Regulated Gateway for Secretion of Invasion Factors in Toxoplasma

Nicholas J. Katris, Giel G. van Dooren, Paul J. McMillan, Eric Hanssen, Leann Tilley, Ross F. Waller

PLOS Pathogens: published April 17, 2014 | https://doi.org/10.1371/journal.ppat.1004074

Rapid Response to Selection, Competitive Release and Increased Transmission Potential of Artesunate-Selected Plasmodium chabaudi Malaria Parasites

Laura C. Pollitt, Silvie Huijben, Derek G. Sim, Rahel M. Salathé, Matthew J. Jones, Andrew F. Read

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004019

Abortive T Follicular Helper Development Is Associated with a Defective Humoral Response in Leishmania infantum-Infected Macaques

Vasco Rodrigues, Mireille Laforge, Laure Campillo-Gimenez, Calaiselvy Soundaramourty, Ana Correia-de-Oliveira, Ricardo Jorge Dinis-Oliveira, Ali Ouaissi, Anabela Cordeiro-da-Silva, Ricardo Silvestre, Jérôme Estaquier

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004096

Concerted Spatio-Temporal Dynamics of Imported DNA and ComE DNA Uptake Protein during Gonococcal Transformation

Heike Gangel, Christof Hepp, Stephanie Müller, Enno R. Oldewurtel, Finn Erik Aas, Michael Koomey, Berenike Maier

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004043

Mast Cells Expedite Control of Pulmonary Murine Cytomegalovirus Infection by Enhancing the Recruitment of Protective CD8 T Cells to the Lungs

Stefan Ebert, Marc Becker, Niels A. W. Lemmermann, Julia K. Büttner, Anastasija Michel, Christian Taube, Jürgen Podlech, Verena Böhm, Kirsten Freitag, Doris Thomas, Rafaela Holtappels, Matthias J. Reddehase, Michael Stassen

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004100

Functionally Redundant RXLR Effectors from Phytophthora infestans Act at Different Steps to Suppress Early flg22-Triggered Immunity

Xiangzi Zheng, Hazel McLellan, Malou Fraiture, Xiaoyu Liu, Petra C. Boevink, Eleanor M. Gilroy, Ying Chen, Kabindra Kandel, Guido Sessa, Paul R. J. Birch, Frédéric Brunner

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004057

HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1

Yanyan Peng, Ruidan Xu, Xiaofeng Zheng

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004041

The Transcriptional Activator LdtR from ‘Candidatus Liberibacter asiaticus’ Mediates Osmotic Stress Tolerance

Fernando A. Pagliai, Christopher L. Gardner, Lora Bojilova, Amanda Sarnegrim, Cheila Tamayo, Anastasia H. Potts, Max Teplitski, Svetlana Y. Folimonova, Claudio F. Gonzalez, Graciela L. Lorca

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004101

JC Polyomavirus Infection Is Strongly Controlled by Human Leucocyte Antigen Class II Variants

Emilie Sundqvist, Dorothea Buck, Clemens Warnke, Eva Albrecht, Christian Gieger, Mohsen Khademi, Izaura Lima Bomfim, Anna Fogdell-Hahn, Jenny Link, Lars Alfredsson, Helle Bach Søndergaard, Jan Hillert, International Multiple Sclerosis Genetics Consortium, Annette B. Oturai, Bernhard Hemme, Ingrid Kockum, Tomas Olsson

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004084

Cationic Antimicrobial Peptides Promote Microbial Mutagenesis and Pathoadaptation in Chronic Infections

Dominique H. Limoli, Andrea B. Rockel, Kurtis M. Host, Anuvrat Jha, Benjamin T. Kopp, Thomas Hollis, Daniel J. Wozniak

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004083

Noncanonical Role for the Host Vps4 AAA+ ATPase ESCRT Protein in the Formation of Tomato Bushy Stunt Virus Replicase

Daniel Barajas, Isabel Fernández de Castro Martín, Judit Pogany, Cristina Risco, Peter D. Nagy

PLOS Pathogens: published April 24, 2014 | https://doi.org/10.1371/journal.ppat.1004087

Corrections

Correction: Preservation of Tetherin and CD4 Counter-Activities in Circulating Vpu Alleles despite Extensive Sequence Variation within HIV-1 Infected Individuals

The PLOS Pathogens Staff

PLOS Pathogens: published April 14, 2014 | https://doi.org/10.1371/journal.ppat.1004118

Correction: Production, Fate and Pathogenicity of Plasma Microparticles in Murine Cerebral Malaria

The PLOS Pathogens Staff

PLOS Pathogens: published April 14, 2014 | https://doi.org/10.1371/journal.ppat.1004119

Correction: Cytomegalovirus m154 Hinders CD48 Cell-Surface Expression and Promotes Viral Escape from Host Natural Killer Cell Control

The PLOS Pathogens Staff

PLOS Pathogens: published April 15, 2014 | https://doi.org/10.1371/journal.ppat.1004121

Correction: Differential Function of Lip Residues in the Mechanism and Biology of an Anthrax Hemophore

The PLOS Pathogens Staff

PLOS Pathogens: published April 15, 2014 | https://doi.org/10.1371/journal.ppat.1004122

Correction: Code-Assisted Discovery of TAL Effector Targets in Bacterial Leaf Streak of Rice Reveals Contrast with Bacterial Blight and a Novel Susceptibility Gene

The PLOS Pathogens Staff

PLOS Pathogens: published April 16, 2014 | https://doi.org/10.1371/journal.ppat.1004126

Correction: Inflammatory Stimuli Reprogram Macrophage Phagocytosis to Macropinocytosis for the Rapid Elimination of Pathogens

The PLOS Pathogens Staff

PLOS Pathogens: published April 16, 2014 | https://doi.org/10.1371/journal.ppat.1004127

Correction: The Secreted Triose Phosphate Isomerase of Brugia malayi Is Required to Sustain Microfilaria Production In Vivo

The PLOS Pathogens Staff

PLOS Pathogens: published April 28, 2014 | https://doi.org/10.1371/journal.ppat.1004133

Correction: Transovarial Transmission of a Plant Virus Is Mediated by Vitellogenin of Its Insect Vector

The PLOS Pathogens Staff

PLOS Pathogens: published April 25, 2014 | https://doi.org/10.1371/journal.ppat.1004141

Correction: Progressive Accumulation of Activated ERK2 within Highly Stable ORF45-Containing Nuclear Complexes Promotes Lytic Gammaherpesvirus Infection

The PLOS Pathogens Staff

PLOS Pathogens: published April 28, 2014 | https://doi.org/10.1371/journal.ppat.1004147

Correction: Tc17 Cells Mediate Vaccine Immunity against Lethal Fungal Pneumonia in Immune Deficient Hosts Lacking CD4⁺ T Cells

The PLOS Pathogens Staff

PLOS Pathogens: published April 28, 2014 | https://doi.org/10.1371/journal.ppat.1004148

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