The use of Christmas Seals to raise money for tuberculosis originated in Denmark in 1903 and served to highlight the profound impact of this disease. Perhaps less well appreciated was the role of the CD8+ T cell (see Lewinsohn et al, e127).
Image Credit: Image modified by David Lewinsohn. With permission ©2007 American Lung Association. For more information about the American Lung Association or to support its work, call 1-800-LUNG-USA (1-800-586-4872) or log on to http://www.lungusa.org/.
Editorial
The Impact of PLoS Pathogens
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030145
Opinion
Botulinum Neurotoxin Heavy Chain Belt as an Intramolecular Chaperone for the Light Chain
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030113
Research Articles
Serum Amyloid P Aids Complement-Mediated Immunity to Streptococcus pneumoniae
PLOS Pathogens: published September 7, 2007 | https://doi.org/10.1371/journal.ppat.0030120
Inhibitors of Pathogen Intercellular Signals as Selective Anti-Infective Compounds
PLOS Pathogens: published September 14, 2007 | https://doi.org/10.1371/journal.ppat.0030126
Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B
PLOS Pathogens: published September 21, 2007 | https://doi.org/10.1371/journal.ppat.0030127
Distinct Roles for Intra- and Extracellular Siderophores during Aspergillus fumigatus Infection
PLOS Pathogens: published September 7, 2007 | https://doi.org/10.1371/journal.ppat.0030128
Hemoglobin Is a Co-Factor of Human Trypanosome Lytic Factor
PLOS Pathogens: published September 7, 2007 | https://doi.org/10.1371/journal.ppat.0030129
Plasmodium falciparum Uses gC1qR/HABP1/p32 as a Receptor to Bind to Vascular Endothelium and for Platelet-Mediated Clumping
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030130
Phylogenetic Analysis Reveals the Global Migration of Seasonal Influenza A Viruses
PLOS Pathogens: published September 14, 2007 | https://doi.org/10.1371/journal.ppat.0030131
Mosquitoes Inoculate High Doses of West Nile Virus as They Probe and Feed on Live Hosts
PLOS Pathogens: published September 14, 2007 | https://doi.org/10.1371/journal.ppat.0030132
Apoptotic Killing of HIV-1–Infected Macrophages Is Subverted by the Viral Envelope Glycoprotein
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030134
T Cells Contain an RNase-Insensitive Inhibitor of APOBEC3G Deaminase Activity
PLOS Pathogens: published September 21, 2007 | https://doi.org/10.1371/journal.ppat.0030135
Members of a Large Retroposon Family Are Determinants of Post-Transcriptional Gene Expression in Leishmania
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030136
Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030138
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Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030139
Viral Oncogene–Induced DNA Damage Response Is Activated in Kaposi Sarcoma Tumorigenesis
PLOS Pathogens: published September 28, 2007 | https://doi.org/10.1371/journal.ppat.0030140