November 2005

Neutrophils are the most abundant white blood cell and the first line of defense against invading microbes. This scanning electron micrograph shows a neutrophil (yellow) engulfing rods of Bacillus anthracis (orange), the etiological agent of anthrax (see Mayer-Scholl et al).

Image Credit: The micrograph was taken by Volker Brinkmann with a Leo 1550 scanning electron microscope.

Opinion

Can Specialized Pathogens Colonize Distantly Related Hosts? Schistosome Evolution as a Case Study

Sara V Brant, Eric S Loker

PLOS Pathogens: published November 25, 2005 | https://doi.org/10.1371/journal.ppat.0010038

Research Articles

The Cell Cycle Independence of HIV Infections Is Not Determined by Known Karyophilic Viral Elements

Masahiro Yamashita, Michael Emerman

PLOS Pathogens: published November 11, 2005 | https://doi.org/10.1371/journal.ppat.0010018

Expression of Procyclin mRNAs during Cyclical Transmission of Trypanosoma brucei

Simon Urwyler, Erik Vassella, Jan Van Den Abbeele, Christina Kunz Renggli, Pat Blundell, J. David Barry, Isabel Roditi

PLOS Pathogens: published November 4, 2005 | https://doi.org/10.1371/journal.ppat.0010022

Human Neutrophils Kill Bacillus anthracis

Anne Mayer-Scholl, Robert Hurwitz, Volker Brinkmann, Monika Schmid, Peter Jungblut, Yvette Weinrauch, Arturo Zychlinsky

PLOS Pathogens: published November 11, 2005 | https://doi.org/10.1371/journal.ppat.0010023

Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases

Sascha Martens, Iana Parvanova, Jens Zerrahn, Gareth Griffiths, Gudrun Schell, Gaby Reichmann, Jonathan C Howard

PLOS Pathogens: published November 18, 2005 | https://doi.org/10.1371/journal.ppat.0010024

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria

Peter C Bull, Matthew Berriman, Sue Kyes, Michael A Quail, Neil Hall, Moses M Kortok, Kevin Marsh, Chris I Newbold

PLOS Pathogens: published November 18, 2005 | https://doi.org/10.1371/journal.ppat.0010026

Mechanisms of Assembly and Cellular Interactions for the Bacterial Genotoxin CDT

Dragana Nesic, C. Erec Stebbins

PLOS Pathogens: published November 18, 2005 | https://doi.org/10.1371/journal.ppat.0010028

Molecular Identification of a Malaria Merozoite Surface Sheddase

Philippa K Harris, Sharon Yeoh, Anton R Dluzewski, Rebecca A O'Donnell, Chrislaine Withers-Martinez, Fiona Hackett, Lawrence H Bannister, Graham H Mitchell, Michael J Blackman

PLOS Pathogens: published November 25, 2005 | https://doi.org/10.1371/journal.ppat.0010029

Aspergillus fumigatus Triggers Inflammatory Responses by Stage-Specific β-Glucan Display

Tobias M Hohl, Heather L. Van Epps, Amariliz Rivera, Laura A Morgan, Patrick L Chen, Marta Feldmesser, Eric G Pamer

PLOS Pathogens: published November 18, 2005 | https://doi.org/10.1371/journal.ppat.0010030

Comparative Signature-Tagged Mutagenesis Identifies Pseudomonas Factors Conferring Resistance to the Pulmonary Collectin SP-A

Shiping Zhang, Yi Chen, Eric Potvin, Francois Sanschagrin, Roger C Levesque, Francis X McCormack, Gee W Lau

PLOS Pathogens: published November 25, 2005 | https://doi.org/10.1371/journal.ppat.0010031

Cover

Neutrophil engulfing Bacillus anthracis