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November 2005

Neutrophils are the most abundant white blood cell and the first line of defense against invading microbes. This scanning electron micrograph shows a neutrophil (yellow) engulfing rods of Bacillus anthracis (orange), the etiological agent of anthrax (see Mayer-Scholl et al).

Image Credit: The micrograph was taken by Volker Brinkmann with a Leo 1550 scanning electron microscope.

Research Articles

Expression of Procyclin mRNAs during Cyclical Transmission of Trypanosoma brucei

Simon Urwyler, Erik Vassella, Jan Van Den Abbeele, Christina Kunz Renggli, Pat Blundell, J. David Barry, Isabel Roditi

Human Neutrophils Kill Bacillus anthracis

Anne Mayer-Scholl, Robert Hurwitz, Volker Brinkmann, Monika Schmid, Peter Jungblut, Yvette Weinrauch, Arturo Zychlinsky

Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases

Sascha Martens, Iana Parvanova, Jens Zerrahn, Gareth Griffiths, Gudrun Schell, Gaby Reichmann, Jonathan C Howard

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria

Peter C Bull, Matthew Berriman, Sue Kyes, Michael A Quail, Neil Hall, Moses M Kortok, Kevin Marsh, Chris I Newbold

Molecular Identification of a Malaria Merozoite Surface Sheddase

Philippa K Harris, Sharon Yeoh, Anton R Dluzewski, Rebecca A O'Donnell, Chrislaine Withers-Martinez, Fiona Hackett, Lawrence H Bannister, Graham H Mitchell, Michael J Blackman

Aspergillus fumigatus Triggers Inflammatory Responses by Stage-Specific β-Glucan Display

Tobias M Hohl, Heather L. Van Epps, Amariliz Rivera, Laura A Morgan, Patrick L Chen, Marta Feldmesser, Eric G Pamer

Comparative Signature-Tagged Mutagenesis Identifies Pseudomonas Factors Conferring Resistance to the Pulmonary Collectin SP-A

Shiping Zhang, Yi Chen, Eric Potvin, Francois Sanschagrin, Roger C Levesque, Francis X McCormack, Gee W Lau

Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine

Nat F Brown, Bruce A Vallance, Brian K Coombes, Yanet Valdez, Bryan A Coburn, B. Brett Finlay

Mycobacterial Mutants with Defective Control of Phagosomal Acidification

Graham R Stewart, Janisha Patel, Brian D Robertson, Aaron Rae, Douglas B Young

NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis

Gerben Ferwerda, Stephen E Girardin, Bart-Jan Kullberg, Lionel Le Bourhis, Dirk J. de Jong, Dennis M. L Langenberg, Reinout van Crevel, Gosse J Adema, Tom H. M Ottenhoff, Jos W. M. Van der Meer, Mihai G Netea