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PLoS Pathogens Issue Image | Vol. 8(12) December 2012

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"Gliding" motility of Toxoplasma gondii.

The movement of the apicomplexan parasite Toxoplasma gondii can appear chaotic and haphazard. However, Z-projection of images captured by video microscopy reveals the rhythmic patterns underlying this chaos (see McCoy et al., doi:10.1371/journal.ppat.1003066). By overlaying a heat map (based on pixel density), the paths parasites take as they move across a surface are vividly highlighted, revealing the three simple types of motility that create such complexity. So-called "twirling" motility appears as bright, starlike shapes; "circular" as looped rings; and "helical" motility as long links of chain.

Image Credit: James M. McCoy, The Walter and Eliza Hall Institute of Medical Research/Department of Medical Biology, University of Melbourne.

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"Gliding" motility of Toxoplasma gondii.

The movement of the apicomplexan parasite Toxoplasma gondii can appear chaotic and haphazard. However, Z-projection of images captured by video microscopy reveals the rhythmic patterns underlying this chaos (see McCoy et al., doi:10.1371/journal.ppat.1003066). By overlaying a heat map (based on pixel density), the paths parasites take as they move across a surface are vividly highlighted, revealing the three simple types of motility that create such complexity. So-called "twirling" motility appears as bright, starlike shapes; "circular" as looped rings; and "helical" motility as long links of chain.

Image Credit: James M. McCoy, The Walter and Eliza Hall Institute of Medical Research/Department of Medical Biology, University of Melbourne.

https://doi.org/10.1371/image.ppat.v08.i12.g001