-
Loading metrics
Open Access
Peer-reviewed
Research Article
Thrombin cleavage of the hepatitis E virus polyprotein at multiple conserved locations is required for genome replication
-
Danielle M. Pierce,
Roles Formal analysis, Investigation, Methodology
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯ -
Frazer J. T. Buchanan,
Roles Formal analysis, Investigation, Methodology
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯ -
Fraser L. Macrae,
Roles Formal analysis, Funding acquisition, Investigation, Methodology, Writing – review & editing
Affiliation Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom
⨯ -
Jake T. Mills,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯ -
Abigail Cox,
Roles Formal analysis, Investigation, Methodology
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯ -
Khadijah M. Abualsaoud,
Roles Formal analysis, Investigation, Methodology
Affiliations School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom, Department of Laboratory and Blood Bank, Al Mikhwah General Hospital, Al Mikhwah, Saudi Arabia
⨯ -
Joseph C. Ward,
Roles Formal analysis, Investigation, Methodology
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯ -
Robert A. S. Ariëns,
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
Affiliation Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom
⨯ -
Mark Harris,
Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯ -
Nicola J. Stonehouse,
Roles Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯ -
Morgan R. Herod
Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: m.r.herod@leeds.ac.uk
Affiliation School of Molecular and Cellular Biology, Faculty of Biological Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
⨯
Thrombin cleavage of the hepatitis E virus polyprotein at multiple conserved locations is required for genome replication
- Danielle M. Pierce,
- Frazer J. T. Buchanan,
- Fraser L. Macrae,
- Jake T. Mills,
- Abigail Cox,
- Khadijah M. Abualsaoud,
- Joseph C. Ward,
- Robert A. S. Ariëns,
- Mark Harris,
- Nicola J. Stonehouse
-
- Published: July 21, 2023
- https://doi.org/10.1371/journal.ppat.1011529