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Open Access
Peer-reviewed
Research Article
Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression
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Qi-Xin Hu,
Roles Investigation, Methodology, Validation
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Hubei Key Laboratory of Cell Homeostasis, Hubei Key Laboratory of Developmentally Originated Disease, Hubei Key Laboratory of Enteropathy, Wuhan University, Wuhan, Hubei, China
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Hui-Yi Wang,
Roles Investigation, Methodology
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Hubei Key Laboratory of Cell Homeostasis, Hubei Key Laboratory of Developmentally Originated Disease, Hubei Key Laboratory of Enteropathy, Wuhan University, Wuhan, Hubei, China
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Lu Jiang,
Roles Investigation
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Hubei Key Laboratory of Cell Homeostasis, Hubei Key Laboratory of Developmentally Originated Disease, Hubei Key Laboratory of Enteropathy, Wuhan University, Wuhan, Hubei, China
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Chen-Yu Wang,
Roles Software
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Hubei Key Laboratory of Cell Homeostasis, Hubei Key Laboratory of Developmentally Originated Disease, Hubei Key Laboratory of Enteropathy, Wuhan University, Wuhan, Hubei, China
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Lin-Gao Ju,
Roles Conceptualization
Affiliation Department of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
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Yuan Zhu,
Roles Conceptualization
Affiliation Department of Biological Repositories, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
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Bo Zhong,
Roles Methodology, Resources
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Department of Immunology, Medical Research Institute, School of Medicine, Wuhan University, Wuhan, China
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Min Wu ,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: wumin@whu.edu.cn (MW); wildman1992@whu.edu.cn (ZW); lilianyun@whu.edu.cn (L-YL)
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Hubei Key Laboratory of Cell Homeostasis, Hubei Key Laboratory of Developmentally Originated Disease, Hubei Key Laboratory of Enteropathy, Wuhan University, Wuhan, Hubei, China
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Zhen Wang ,
Roles Investigation, Validation, Writing – original draft
* E-mail: wumin@whu.edu.cn (MW); wildman1992@whu.edu.cn (ZW); lilianyun@whu.edu.cn (L-YL)
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Hubei Key Laboratory of Cell Homeostasis, Hubei Key Laboratory of Developmentally Originated Disease, Hubei Key Laboratory of Enteropathy, Wuhan University, Wuhan, Hubei, China
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Lian-Yun Li
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: wumin@whu.edu.cn (MW); wildman1992@whu.edu.cn (ZW); lilianyun@whu.edu.cn (L-YL)
Affiliations Frontier Science Center for Immunology and Metabolism, College of Life Sciences, Wuhan University, Wuhan, Hubei, China, Hubei Key Laboratory of Cell Homeostasis, Hubei Key Laboratory of Developmentally Originated Disease, Hubei Key Laboratory of Enteropathy, Wuhan University, Wuhan, Hubei, China
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Histone demethylase LSD1 promotes RIG-I poly-ubiquitination and anti-viral gene expression
- Qi-Xin Hu,
- Hui-Yi Wang,
- Lu Jiang,
- Chen-Yu Wang,
- Lin-Gao Ju,
- Yuan Zhu,
- Bo Zhong,
- Min Wu,
- Zhen Wang,
- Lian-Yun Li
- Published: September 16, 2021
- https://doi.org/10.1371/journal.ppat.1009918