Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

• Pachiyappan Kamarajan,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, CA, United States of America, Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, United States of America

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• Islam Ateia,

  Roles Formal analysis, Methodology

  Affiliation Department of Oral Medicine and Periodontology, Mansoura University, Mansoura, Egypt

  http://orcid.org/0000-0001-8060-2965

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• Jae M. Shin,

  Roles Writing – review & editing

  Affiliations Department of Cariology, Restorative Sciences, and Endodontics, School of Dentistry, University of Michigan, Ann Arbor, MI, United States of America, Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, United States of America

  http://orcid.org/0000-0003-0491-315X

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• J. Christopher Fenno,

  Roles Writing – review & editing

  Affiliation Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann arbor, MI, United States of America

  http://orcid.org/0000-0002-7073-7855

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• Charles Le,

  Roles Methodology

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, CA, United States of America

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• Ling Zhan,

  Roles Resources, Writing – review & editing

  Affiliation Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, CA, United States of America

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• Ana Chang,

  Roles Resources

  Affiliation Department of Periodontics, Oral Health Sciences, School of Dentistry, University of Washington, Seattle, WA, United States of America

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• Richard Darveau,

  Roles Resources

  Affiliation Department of Periodontics, Oral Health Sciences, School of Dentistry, University of Washington, Seattle, WA, United States of America

  http://orcid.org/0000-0002-3559-7383

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• Yvonne L. Kapila

  Roles Conceptualization, Data curation, Validation, Writing – review & editing

  * E-mail: Yvonne.Kapila@ucsf.edu

  Affiliations Department of Orofacial Sciences, School of Dentistry, University of California, San Francisco, CA, United States of America, Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, United States of America

  http://orcid.org/0000-0003-1330-0654

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