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Open Access
Peer-reviewed
Research Article
Modeling the measles paradox reveals the importance of cellular immunity in regulating viral clearance
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Sinead E. Morris ,
Roles Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
* E-mail: sinead.morris@columbia.edu
Current address: Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA
Affiliation Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA
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Andrew J. Yates,
Roles Investigation, Methodology, Writing – review & editing
Affiliation Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA
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Rik L. de Swart,
Roles Investigation, Writing – review & editing
Affiliation Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands
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Rory D. de Vries,
Roles Investigation, Writing – review & editing
Affiliation Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands
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Michael J. Mina,
Roles Investigation, Writing – review & editing
Affiliation Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
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Ashley N. Nelson,
Roles Investigation, Writing – review & editing
Current address: Department of Pediatrics and Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA
Affiliation Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
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Wen-Hsuan W. Lin,
Roles Data curation, Writing – review & editing
Current address: Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA
Affiliation Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
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Roger D. Kouyos,
Roles Investigation, Writing – review & editing
Affiliations Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Switzerland
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Diane E. Griffin ,
Contributed equally to this work with: Diane E. Griffin, Bryan T. Grenfell
Roles Conceptualization, Data curation, Supervision, Writing – review & editing
Affiliation Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
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Bryan T. Grenfell
Contributed equally to this work with: Diane E. Griffin, Bryan T. Grenfell
Roles Conceptualization, Methodology, Supervision, Writing – review & editing
Affiliations Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA, Fogarty International Center, National Institutes of Health, Bethesda, MD, USA
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Modeling the measles paradox reveals the importance of cellular immunity in regulating viral clearance
- Sinead E. Morris,
- Andrew J. Yates,
- Rik L. de Swart,
- Rory D. de Vries,
- Michael J. Mina,
- Ashley N. Nelson,
- Wen-Hsuan W. Lin,
- Roger D. Kouyos,
- Diane E. Griffin,
- Bryan T. Grenfell
- Published: December 28, 2018
- https://doi.org/10.1371/journal.ppat.1007493