A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis

Open Access

Peer-reviewed

Research Article

Leslie Goo,

Affiliation Viral Pathogenesis Section, National Institutes of Health, Bethesda, MD, United States of America
⨯
Laura A. VanBlargan,

Affiliation Departments of Medicine, Molecular Microbiology, Pathology & Immunology, and The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, United States of America
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Kimberly A. Dowd,

Affiliation Viral Pathogenesis Section, National Institutes of Health, Bethesda, MD, United States of America
⨯
Michael S. Diamond,

Affiliation Departments of Medicine, Molecular Microbiology, Pathology & Immunology, and The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Theodore C. Pierson

* E-mail: piersontc@mail.nih.gov

Affiliation Viral Pathogenesis Section, National Institutes of Health, Bethesda, MD, United States of America

http://orcid.org/0000-0002-3795-4348

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West Nile virus
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Antibodies
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Virions
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Dengue virus
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Flaviviruses
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Viral structure
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Monoclonal antibodies
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Antigens
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