A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity

Jan Balzarini; Graciela Andrei; Emanuela Balestra; Dana Huskens; Christophe Vanpouille; Andrea Introini; Sonia Zicari; Sandra Liekens; Robert Snoeck; Antonín Holý; Carlo-Federico Perno; Leonid Margolis; Dominique Schols

doi:10.1371/journal.ppat.1003456

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Open Access

Peer-reviewed

Research Article

A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity

Jan Balzarini ,

* E-mail: jan.balzarini@rega.kuleuven.be

Affiliation Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
⨯
Graciela Andrei,

Affiliation Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
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Emanuela Balestra,

Affiliation Department of Experimental Medicine and Biochemical Science, University of Roma Tor Vergata, Rome, Italy
⨯
Dana Huskens,

Affiliation Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
⨯
Christophe Vanpouille,

Affiliation Program of Physical Biology, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Andrea Introini,

Affiliation Program of Physical Biology, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Sonia Zicari,

Affiliation Program of Physical Biology, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Sandra Liekens,

Affiliation Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
⨯
Robert Snoeck,

Affiliation Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
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Antonín Holý ,

¶Professor Antonín Holý suddenly died on July 16, 2012. The co-authors would like to dedicate this paper to his memory.

Affiliation Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czech Republic
⨯
Carlo-Federico Perno,

Affiliation Department of Experimental Medicine and Biochemical Science, University of Roma Tor Vergata, Rome, Italy
⨯
Leonid Margolis,

Affiliation Program of Physical Biology, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Dominique Schols

Affiliation Rega Institute for Medical Research, KU Leuven, Leuven, Belgium
⨯

A Multi-targeted Drug Candidate with Dual Anti-HIV and Anti-HSV Activity

Jan Balzarini,
Graciela Andrei,
Emanuela Balestra,
Dana Huskens,
Christophe Vanpouille,
Andrea Introini,
Sonia Zicari,
Sandra Liekens,
Robert Snoeck,
Antonín Holý

Published: July 25, 2013
https://doi.org/10.1371/journal.ppat.1003456

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