Inhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence

• Carlos Maluquer de Motes,

  Affiliation Department of Virology, Faculty of Medicine, Imperial College London, London, United Kingdom

  ⨯
• Samantha Cooray ,

  Contributed equally to this work with: Samantha Cooray, Hongwei Ren

  Current address: Molecular Immunology Unit, Institute of Child Health, University College London, London, United Kingdom

  Affiliation Department of Virology, Faculty of Medicine, Imperial College London, London, United Kingdom

  ⨯
• Hongwei Ren ,

  Contributed equally to this work with: Samantha Cooray, Hongwei Ren

  Affiliation Department of Virology, Faculty of Medicine, Imperial College London, London, United Kingdom

  ⨯
• Gabriel M. F. Almeida,

  Current address: Laboratório de Vírus, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

  Affiliation Department of Virology, Faculty of Medicine, Imperial College London, London, United Kingdom

  ⨯
• Kieran McGourty,

  Current address: Centre for Molecular Microbiology and Infection, Imperial College London, London, United Kingdom

  Affiliation Department of Virology, Faculty of Medicine, Imperial College London, London, United Kingdom

  ⨯
• Mohammad W. Bahar,

  Affiliation The Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• David I. Stuart,

  Affiliations The Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Science Division, Diamond Light Source, Didcot, United Kingdom

  ⨯
• Jonathan M. Grimes,

  Affiliations The Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Science Division, Diamond Light Source, Didcot, United Kingdom

  ⨯
• Stephen C. Graham,

  Current address: Cambridge Institute for Medical Research and Department of Clinical Biochemistry, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom

  Affiliation The Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

  ⨯
• Geoffrey L. Smith

  * E-mail: geoffrey.l.smith@imperial.ac.uk

  Affiliation Department of Virology, Faculty of Medicine, Imperial College London, London, United Kingdom

  ⨯