The Expanding Functions of Cellular Helicases: The Tombusvirus RNA Replication Enhancer Co-opts the Plant eIF4AIII-Like AtRH2 and the DDX5-Like AtRH5 DEAD-Box RNA Helicases to Promote Viral Asymmetric RNA Replication

Nikolay Kovalev; Peter D. Nagy

doi:10.1371/journal.ppat.1004051

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Peer-reviewed

Research Article

The Expanding Functions of Cellular Helicases: The Tombusvirus RNA Replication Enhancer Co-opts the Plant eIF4AIII-Like AtRH2 and the DDX5-Like AtRH5 DEAD-Box RNA Helicases to Promote Viral Asymmetric RNA Replication

Nikolay Kovalev,

Affiliation Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, United States of America
⨯
Peter D. Nagy

* E-mail: pdnagy2@uky.edu

Affiliation Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, United States of America
⨯

The Expanding Functions of Cellular Helicases: The Tombusvirus RNA Replication Enhancer Co-opts the Plant eIF4AIII-Like AtRH2 and the DDX5-Like AtRH5 DEAD-Box RNA Helicases to Promote Viral Asymmetric RNA Replication

Nikolay Kovalev,
Peter D. Nagy

Published: April 17, 2014
https://doi.org/10.1371/journal.ppat.1004051

About the Authors

Nikolay Kovalev

Affiliation Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, United States of America

Peter D. Nagy

* E-mail: pdnagy2@uky.edu

Affiliation Department of Plant Pathology, University of Kentucky, Lexington, Kentucky, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NK PDN. Performed the experiments: NK. Analyzed the data: NK PDN. Contributed reagents/materials/analysis tools: NK PDN. Wrote the paper: NK PDN.

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Helicases
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Yeast
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Viral replication
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RNA synthesis
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DEAD-box
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RNA helicases
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Saccharomyces cerevisiae
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Yeast infections
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