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Sequencing techniques

Single-cell RNA-seq and machine learning identify HMGN2 as a lactylation-associated hub gene in heart failure

Anzhen Xu, Yanbo Li, Qing Gong, Hanrui Sun, Jiayu Shi, Jingyu Li, Pengyang Gu, Jixu Shi, Xiang Li, Qi Lu

published 21 Sep 2026

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Shotgun metagenomic profiling of the fecal microbiome in Lamp2 knockout mice reveals limited genotype-associated differences under standard housing

Maria Emfietzoglou, Maria Anna Bantounou, Shewa Osmani, Toshio Narimatsu, Konstantinos G. Baroutis, Alexandra Varsamidaki, Dimitra Skondra, Dimitris Papaconstantinou, Panagiotis Theodossiadis, Irini Chatziralli, Joan W. Miller, Demetrios G. Vavvas

published 18 Sep 2026

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The changing landscape of Fabry disease: Impact of the inclusion of the GLA-gene in broader NGS or WES based panels on the phenotypic spectrum

Laura van Dussen, Emilie V. Albers, Saskia N. van der Crabben, Ronald H. Lekanne Deprez, Astrid S. Plomp, Mirjam Langeveld

published 16 Sep 2026

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Diversity at the HYP1 locus in potato cyst nematodes does not result from developmentally-programmed somatic mutations

Vincent C. T. Hanlon, Unnati Sonawala, Cian A. A. Raza, Luisa Kalkert, George Harpum, Lukas A. Burkhardt, Johannes Helder, Sebastian Eves-van den Akker

published 15 Sep 2026

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Metagenomic sequencing in encephalitis diagnostics: Challenges and opportunities in clinical settings

Erika Stentoft, Josefin Olausson, Emilio Rudbeck, Marie Studahl, Hedvig E. Jakobsson

published 15 Sep 2026

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A novel one-step multiplex PCR method (OS-MPCR) for efficient NGS library preparation in cancer

Haiyan Feng, Xiao Hu, Lei Zhang, Qi Zhang, Shuocun Wang, Bingqing Lv, Yufeng Zhang, Dong Shi, Ping Zhou

published 15 Sep 2026

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Streamlining recombinant peptide and protein production using a pre-configured elastin-like polypeptide expression cassette

Jetson Lobos, Jeffrey Velasquez, Fariborz Nasertorabi

published 11 Sep 2026

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Mutations in the N-glycan branching enzyme MGAT1 promote invasiveness and EGF-stimulated proliferation and adhesion in neuroblastoma cells

M. Kristen Hall, Lyla J. Walker, Abel R. Messer, Ruth A. Schwalbe

published 10 Sep 2026

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Correlation assessment of SARS-CoV-2 variants and their subvariants present in clinical and wastewater samples in Oregon, USA (February 7, 2021 - February 26, 2022) using the Freyja bioinformatics approach

Anirudh Bhatia, Justin Elser, Steven J. Carrell, Brent Kronmiller, Melissa Sutton, Christine Kelly, Tyler S. Radniecki

published 09 Sep 2026

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OligoSeq: Rapid nanopore-sequencing of single-stranded oligonucleotides

Robert Ramirez-Garcia, Akashaditya Das, Patrycja Sokolowska, Thomas Heinis

published 03 Sep 2026

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Methods for cost-efficient, whole genome sequencing surveillance for enhanced detection of outbreaks in a hospital setting

Kady D. Waggle, Marissa Pacey Griffith, Alecia B. Rokes, Vatsala Rangachar Srinivasa, Erin M. Nawrocki, Deena Ereifej, Rose Patrick, Hunter Coyle, Shurmin Chaudhary, Nathan J. Raabe, Kathleen Shutt, Alexander J. Sundermann, Vaughn S. Cooper, Lee H. Harrison, Lora Lee Pless

published 01 Sep 2026

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Revisiting differential expression analysis: An updated six-dimensional comparative study

Jianxiong Wu, Shaoke Lu, Hui Yao, Zhaoyuan Fang

published 26 Aug 2026

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Transcriptome analysis of hepatopancreas of Litopenaeus vannamei after acute exposure to Alexandrium pacificum

Fuyuan Zeng, Haiming Chen, Huijie Yang, Tong Li, Hui Huang, Shafira Citra Desrika Putri, Zhangxi Hu, Yulei Zhang

published 25 Aug 2026

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