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Membrane receptor signaling

Lipopolysaccharide-induced alterations in barrier integrity and inflammatory signaling in porcine small intestinal organoids

Sumin Park, Boram Lee, Dahye Kim, Sheet Sunirmal, Min Gook Lee, Haesun Lee, Sun A. Ock, Jae Gyu Yoo

published 01 Oct 2026

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Safety profile of entrectinib in NSCLC: Multi-source pharmacovigilance analysis using FAERS and JADER

JiaLe Yang, JiaWen Liu, GuanBo Zhao, HeChen Li, Ge Sun

published 15 Sep 2026

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Nasal exposure to PM2.5 induces testicular injury and activation of pyroptosis-related signaling in rats: Inhibitor intervention and public transcriptomic analysis

Yi Luo, Cao Wang, Mengxi Tian, Guangyou Lang, Kaixin Li, Zhongyan Zhang, Yu Chu, Qing Xiao, Ma Hong

published 15 Sep 2026

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A multimodal analysis suggests partial IRF8/TLR7-associated myeloid transcriptional convergence between diabetic kidney disease and Parkinson’s disease

Xue Hu, Yingzhuo Li, Bosheng Luo, Yang Wang, Chunjuan Xia, Jiaping Wang

published 20 Aug 2026

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Molecular regulatory mechanism of TRPV4-mediated calcium-dependent 5-HT secretion from enterochromaffin cells and its involvement in ulcerative colitis

Shuo Tong, Yujuan Wang, Jianxin Wang, Chengxin Qu, Shude Pang, Wenwen Zhao, Hui Dong

published 13 Aug 2026

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Functional CCR7A-mediated cellular responses are negatively modulated by the splice variant CCR7B

Minyeong Cho, Hee-Kyung Park, Lan Phuong Nguyen, Thai Uy Nguyen, Duc Trung Nguyen, Soyeon In, Sunghoon Hurh, Beom Jin Park, Jae Young Seong, Jong-Ik Hwang

published 04 Aug 2026

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FAERS-based pharmacovigilance and network toxicology analysis of esomeprazole-associated osteoporosis

Yan Wang, Xiaolong Xu, Guanjun Huang, Hongyan Zhu, Xuan Li, Jue Lin

published 04 Aug 2026

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Concordant RNA-protein evidence and human tissue metabolomics prioritize UPP1-associated nucleotide remodeling in prostate cancer

Xuancai Chen, Wei Su, Qun Zhou, Yucheng Qi, Juanjuan Xie, Yachun Tang, Xin Tang, Hao Fu

published 31 Jul 2026

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Overexpression of CD97 in intestinal epithelial cells attenuates LPS-induced pro-inflammatory cytokine induction via stabilization of β-catenin early in life

Niklas Dressler, Steffi Mayer, Thomas Wiemers, Florentine Weise, Xiaoyan Feng, Gabriela Aust, Nicole Peukert, Martin Lacher, Jan Riedel

published 30 Jul 2026

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Bisphenol A exposure in myasthenia gravis: Potential targets and mechanisms revealed by network toxicology and molecular dynamics

Shupeng Wu, Yaoqi Wu, Li Zhang, Jun Zhu

published 28 Jul 2026

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Signal mining and analysis of adverse events associated with Isotretinoin: A 20-Year real-world pharmacovigilance study based on FAERS and EudraVigilance databases

Qian Chen, JinYue Li, Mao Zhang, XueDong Kang, LiZhu Han, Yuan Bian, HongLi Luo

published 16 Jul 2026

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Mycobacterial lipoarabinomannan negatively interferes with macrophage responses to Aspergillus fumigatus in-vitro

Luis E. Gonzales-Huerta, Thomas J. Williams, Renad Aljohani, Brian Robertson, Carlton A. Evans, Darius P. H. Armstrong-James

published 09 Jul 2026

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AI-driven molecular diversification and ligand-based optimization of macitentan derivatives targeting VEGFR1 and endothelin signaling pathways

Sümeyra Koç Sahin, Nouman Ali

published 30 Jun 2026

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