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Guide RNA

Proinsulin degradation and presentation of a proinsulin B-chain autoantigen involves ER-associated protein degradation (ERAD)-enzyme UBE2G2

Tom Cremer, Hanneke Hoelen, [ ... ], Emmanuel J. H. J. Wiertz

Non-replicative phage particles delivering CRISPR-Cas9 to target major bla_CTX-M variants

Naiyaphat Nittayasut, Teerapong Yata, [ ... ], Pattrarat Chanchaithong

Fusion of histone variants to Cas9 suppresses non-homologous end joining

Tomoko Kato-Inui, Gou Takahashi, Terumi Ono, Yuichiro Miyaoka

PHF2 regulates sarcomeric gene transcription in myogenesis

Taku Fukushima, Yuka Hasegawa, [ ... ], Iori Sakakibara

Clinical validation of RCSMS: A rapid and sensitive CRISPR-Cas12a test for the molecular detection of SARS-CoV-2 from saliva

Joaquín Abugattas-Núñez del Prado, Angélica Quintana Reyes, [ ... ], Edward Málaga-Trillo

Ryegrass mottle virus complete genome determination and development of infectious cDNA by combining two methods– 3′ RACE and RNA-Seq

Ina Balke, Ivars Silamikelis, [ ... ], Andris Zeltins

Predicting CRISPR-Cas12a guide efficiency for targeting using machine learning

Aidan O’Brien, Denis C. Bauer, Gaetan Burgio

Endogenous expression of inactive lysine deacetylases reveals deacetylation-dependent cellular mechanisms

Tasha B. Toro, Elena V. Skripnikova, [ ... ], Terry J. Watt

Engineering conjugative CRISPR-Cas9 systems for the targeted control of enteric pathogens and antibiotic resistance

Haiqing Sheng, Sarah Wu, [ ... ], Scott A. Minnich

GreenGate 2.0: Backwards compatible addons for assembly of complex transcriptional units and their stacking with GreenGate

Marcel Piepers, Katarina Erbstein, [ ... ], Alexis Maizel

Cardiac RNase Z edited via CRISPR-Cas9 drives heart hypertrophy in Drosophila

Ekaterina Migunova, Saathvika Rajamani, [ ... ], Edward B. Dubrovsky

Structure of the T. brucei kinetoplastid RNA editing substrate-binding complex core component, RESC5

Raul Salinas, Emily Cannistraci, Maria A. Schumacher

In vitro genome editing activity of Cas9 in somatic cells after random and transposon-based genomic Cas9 integration

Jenny-Helena Söllner, Hendrik Johannes Sake, [ ... ], Björn Petersen

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