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Guide RNA

Super-enhancer acquisition drives oncogene expression in triple negative breast cancer

Ryan Raisner, Russell Bainer, [ ... ], Karen E. Gascoigne

Constructing a human complex type N-linked glycosylation pathway in Kluyveromyces marxianus

Ming-Hsuan Lee, Tsui-Ling Hsu, [ ... ], Wen-Hsiung Li

TIM, a targeted insertional mutagenesis method utilizing CRISPR/Cas9 in Chlamydomonas reinhardtii

Tyler Picariello, Yuqing Hou, [ ... ], George B. Witman

SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity

Derek Cerchione, Katherine Loveluck, [ ... ], Barrett E. Steinberg

CRISPR/Cas9-targeting of CD40 in hematopoietic stem cells limits immune activation mediated by anti-CD40

Rui Wang, Sean Graham, [ ... ], Jijie Gu

CRISPR-mediated accelerated domestication of African rice landraces

Elia Lacchini, Edward Kiegle, [ ... ], Martin M. Kater

An improved strategy for CRISPR/Cas9 gene knockout and subsequent wildtype and mutant gene rescue

Jiankang Jin, Yan Xu, [ ... ], Jaffer A. Ajani

Are the current gRNA ranking prediction algorithms useful for genome editing in plants?

Fatima Naim, Kylie Shand, [ ... ], Peter M. Waterhouse

Tankyrase inhibition sensitizes cells to CDK4 blockade

Miguel Foronda, Yusuke Tarumoto, [ ... ], Lukas E. Dow

High throughput, efficacious gene editing & genome surveillance in Chinese hamster ovary cells

S. C. Huhn, Y. Ou, [ ... ], Z. Du

Multiplexed editing of a begomovirus genome restricts escape mutant formation and disease development

Anirban Roy, Ying Zhai, [ ... ], Hanu R. Pappu

Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient

Sophie Dal-Pra, Conrad P. Hodgkinson, Victor J. Dzau

CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein

Milad Babaei, Yuekun Liu, [ ... ], Thomas D. Gilmore

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