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Genetically modified organisms

Microvillous cells in the olfactory epithelium express elements of the solitary chemosensory cell transduction signaling cascade

Federica Genovese, Marco Tizzano

published 13 Sep 2018

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Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality

Arturo Orlacchio, Aaron E. Stark, Claudia Foray, Foued Amari, Tyler Sheetz, Erika Reese, Anna Tessari, Krista La Perle, Dario Palmieri, Philip N. Tsichlis, Vincenzo Coppola

published 12 Sep 2018

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Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice

Eike A. Strathmann, Miriam Peters, Seyyedmohsen Hosseinibarkooie, Frank W. Rigo, C. Frank Bennett, Phillip G. Zaworski, Karen S. Chen, Michael Nothnagel, Brunhilde Wirth

published 06 Sep 2018

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The immunomodulatory quinoline-3-carboxamide paquinimod reverses established fibrosis in a novel mouse model for liver fibrosis

Nina Fransén Pettersson, Adnan Deronic, Julia Nilsson, Tine D. Hannibal, Lisbeth Hansen, Anja Schmidt-Christensen, Fredrik Ivars, Dan Holmberg

published 05 Sep 2018

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Endogenous tassel-specific small RNAs-mediated RNA interference enables a novel glyphosate-inducible male sterility system for commercial production of hybrid seed in Zea mays L.

Heping Yang, Youlin Qi, Mike E. Goley, Jintai Huang, Sergey Ivashuta, Yuanji Zhang, Oscar C. Sparks, Jiyan Ma, Brook M. van Scoyoc, Amy L. Caruano-Yzermans, Jennifer King-Sitzes, Xin Li, Aihong Pan, Martin A. Stoecker, B. Elizabeth Wiggins, Marguerite J. Varagona

published 23 Aug 2018

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(Pro)Renin receptor mediates obesity-induced antinatriuresis and elevated blood pressure via upregulation of the renal epithelial sodium channel

Syed S. Quadri, Silas Culver, Nrupama Ramkumar, Donald E. Kohan, Helmy M. Siragy

published 17 Aug 2018

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A novel recombinant human plasminogen activator: Efficient expression and hereditary stability in transgenic goats and in vitro thrombolytic bioactivity in the milk of transgenic goats

Zhengyi He, Rui Lu, Ting Zhang, Lei Jiang, Minya Zhou, Daijin Wu, Yong Cheng

published 17 Aug 2018

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TAK-272 (imarikiren), a novel renin inhibitor, improves cardiac remodeling and mortality in a murine heart failure model

Tomoya Hara, Satoshi Nishimura, Toshihiro Yamamoto, Yumiko Kajimoto, Keiji Kusumoto, Ray Kanagawa, Shota Ikeda, Tomoyuki Nishimoto

published 09 Aug 2018

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Exploring potential roles for the interaction of MOM1 with SUMO and the SUMO E3 ligase-like protein PIAL2 in transcriptional silencing

Qiu-Yuan Zhao, Xin-Jian He

published 09 Aug 2018

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Overexpression of the rice gene OsSIZ1 in Arabidopsis improves drought-, heat-, and salt-tolerance simultaneously

Neelam Mishra, Anurag P. Srivastava, Nardana Esmaeili, Wenjun Hu, Guoxin Shen

published 09 Aug 2018

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Neurog3 misexpression unravels mouse pancreatic ductal cell plasticity

Andhira Vieira, Bastien Vergoni, Monica Courtney, Noémie Druelle, Elisabet Gjernes, Biljana Hadzic, Fabio Avolio, Tiziana Napolitano, Sergi Navarro Sanz, Ahmed Mansouri, Patrick Collombat

published 09 Aug 2018

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Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis

Matthew Cummings, Anitha Christy Sigamani Arumanayagam, Picheng Zhao, Sunil Kannanganat, Olaf Stuve, Nitin J. Karandikar, Todd N. Eagar

published 08 Aug 2018

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Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3

Bernd O. Evert, Rohit Nalavade, Johannes Jungverdorben, Frank Matthes, Stephanie Weber, Ashish Rajput, Stefan Bonn, Oliver Brüstle, Michael Peitz, Sybille Krauß

published 07 Aug 2018

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