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Genetically modified animals

Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechano-adaptation

Mariana Moraes de Lima Perini, Alyssa F. Fayemi, [ ... ], Jiliang Li

A novel genetic strategy to interrogate an unknown phenotypic modifier: Sdhc KO-Robertsonian mice develop frequent thyroid abnormalities with papillary thyroid carcinoma-like features

Jean-Pierre Bayley, Heggert G. Rebel, Peter Devilee

The METTL3 inhibitor STM2457 suppresses gastric cancer progression by modulating m⁶A RNA modification

Hang Sun, Haozhi Xu, [ ... ], Chao Xu

Age-associated accumulation of carbamylation-derived products in tissues is independent from the myeloperoxidase pathway in mice

Christine Pietrement, Anaïs Okwieka, [ ... ], Stéphane Jaisson

Salt loading as a promising approach to study the dopaminergic phenotype of neurons of the supraoptic nucleus in mice

Alyona E. Bannikova, Tatiana S. Pronina, [ ... ], Michael V. Ugrumov

Mixed effects of complement in a chronic murine model of inflammatory erosive arthritis and pulmonary vascular disease

Kiana L. Chen, Stacey Duemmel, [ ... ], Homaira Rahimi

Molecular remodeling of the myocardium in mice with melanocortin-4 receptor deletion before cardiac function impairment

Xiaomei Wang, Yuanmin Qi, [ ... ], Jinxiang Yuan

PFKFB3 exacerbates myocardial injury by accelerating CXCR4^hi neutrophil mobilization after acute myocardial infarction

Yingjia Xu, Min Xiao, [ ... ], Zongying Yu

Generation and characterization of a mouse model of conditional Chd4 knockout in the endometrial epithelium

Shannon K. Harkins, Hilary J. Skalski, [ ... ], Ronald L. Chandler

Development of a floxed Gabbr2 gene allows for widespread conditional disruption of GABBR2 and recapitulates the phenotype of germline Gabbr2 knockout mice

Julie Rose Hens, Stacey Brown, [ ... ], John J. Wysolmerski

UTX/Top2β axis mediated spinal cord microvascular endothelial cells senescence exacerbates spinal cord injury

Dongliang Liu, Yudong Liu, Tianding Wu, Jianzhong Hu

Conditional deletion of Tmem63b does not impact mouse voiding behavior

Marianela G. Dalghi, Wily G. Ruiz, [ ... ], Gerard Apodaca

Renal and hepatic function is preserved following inducible knockout of kynurenine pathway enzymes KMO or QPRT in adult mice

Benjamin S. Summers, Luke Milham, [ ... ], Bruce J. Brew

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