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Genetic engineering

Primary cilia in osteoblasts and osteocytes are required for skeletal development and mechano-adaptation

Mariana Moraes de Lima Perini, Alyssa F. Fayemi, [ ... ], Jiliang Li

A novel genetic strategy to interrogate an unknown phenotypic modifier: Sdhc KO-Robertsonian mice develop frequent thyroid abnormalities with papillary thyroid carcinoma-like features

Jean-Pierre Bayley, Heggert G. Rebel, Peter Devilee

The METTL3 inhibitor STM2457 suppresses gastric cancer progression by modulating m⁶A RNA modification

Hang Sun, Haozhi Xu, [ ... ], Chao Xu

Food and feed safety of a novel Vip3C insecticidal protein derived from Paenibacillus spp. for protection of crop plants against key Lepidopteran pests

Lucas J. McKinnon, Rong Wang, [ ... ], Tianbo Xu

Age-associated accumulation of carbamylation-derived products in tissues is independent from the myeloperoxidase pathway in mice

Christine Pietrement, Anaïs Okwieka, [ ... ], Stéphane Jaisson

Choosing the best route: Comparative optimization of wheat transformation methods for improving yield by targeting TaARE1-D with CRISPR/Cas9

Mumin Ibrahim Tek, Kubra Budak Tek, [ ... ], Hakan Fidan

Salt loading as a promising approach to study the dopaminergic phenotype of neurons of the supraoptic nucleus in mice

Alyona E. Bannikova, Tatiana S. Pronina, [ ... ], Michael V. Ugrumov

Mixed effects of complement in a chronic murine model of inflammatory erosive arthritis and pulmonary vascular disease

Kiana L. Chen, Stacey Duemmel, [ ... ], Homaira Rahimi

Molecular remodeling of the myocardium in mice with melanocortin-4 receptor deletion before cardiac function impairment

Xiaomei Wang, Yuanmin Qi, [ ... ], Jinxiang Yuan

PFKFB3 exacerbates myocardial injury by accelerating CXCR4^hi neutrophil mobilization after acute myocardial infarction

Yingjia Xu, Min Xiao, [ ... ], Zongying Yu

HEDGES co-prevents both SARS-CoV-2 and pandemic influenza infection in mice by rapid, durable co-production of twelve different anti-pandemic monoclonal antibodies

Marissa Mack, Alice Ye, [ ... ], Robert Debs

Monitoring of Cd and GSH contents and Bn-OASTL expression in transgenic tobacco seedlings in response to Cd stress

Xiaolan He, Jianwei Wang, Wenxu Li, Xinhong Chen

Effects of combination therapy of a CDK4/6 and MEK inhibitor in diffuse midline glioma preclinical models

Yusuke Tomita, Gabrielle Link, [ ... ], Oren J. Becher

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