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Genetically modified organisms

Oxidant resistant human apolipoprotein A-I functions similarly to the unmodified human isoform in delaying atherosclerosis progression and promoting atherosclerosis regression in hyperlipidemic mice

Emmanuel Opoku, Stela Berisha, Gregory Brubaker, Peggy Robinet, Jonathan D. Smith

published 04 Feb 2022

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Founder transformants of cotton (Gossypium hirsutum L.) obtained through the introduction of DS-Red, Rec, Rep and CRISPR/Cas9 expressing constructs for developing base lines of recombinase mediated gene stacking

Sabin Aslam, Sultan Habibullah Khan, Aftab Ahmad, Sriema Lalani Walawage, Abhaya M. Dandekar

published 03 Feb 2022

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Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

Chunxing Yang, Tao Qiao, Jia Yu, Hongyan Wang, Yansu Guo, Johnny Salameh, Jake Metterville, Sepideh Parsi, Issa Yusuf, Robert H. Brown, Huaibin Cai, Zuoshang Xu

published 03 Feb 2022

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Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosis

Katherine R. Sadleir, Jelena Popovic, Ammaarah Khatri, Robert Vassar

published 02 Feb 2022

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Chronic spinal cord injury functionally repaired by direct implantation of encapsulated hair-follicle-associated pluripotent (HAP) stem cells in a mouse model: Potential for clinical regenerative medicine

Koya Obara, Kyoumi Shirai, Yuko Hamada, Nobuko Arakawa, Michiko Yamane, Nanako Takaoka, Ryoichi Aki, Robert M. Hoffman, Yasuyuki Amoh

published 27 Jan 2022

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Transgenic overexpression of CTRP3 does not prevent alcohol induced hepatic steatosis in female mice

Kristy L. Thomas, Callie L. Root, Jonathan M. Peterson

published 07 Jan 2022

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Beneficial impact of Ac3IV, an AVP analogue acting specifically at V1a and V1b receptors, on diabetes islet morphology and transdifferentiation of alpha- and beta-cells

Shruti Mohan, Ryan Lafferty, Neil Tanday, Peter R. Flatt, R. Charlotte Moffett, Nigel Irwin

published 20 Dec 2021

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Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting

Bernard Lassègue, Sandeep Kumar, Rohan Mandavilli, Keke Wang, Michelle Tsai, Dong-Won Kang, Catherine Demos, Marina S. Hernandes, Alejandra San Martín, W. Robert Taylor, Hanjoong Jo, Kathy K. Griendling

published 20 Dec 2021

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Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice

Carla Casu, Alison Liu, Gianluca De Rosa, Audrey Low, Aae Suzuki, Sayantani Sinha, Yelena Z. Ginzburg, Charles Abrams, Mariam Aghajan, Shuling Guo, Stefano Rivella

published 10 Dec 2021

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Phenotypic effects from the expression of a deregulated AtGAD1 transgene and GABA pathway suppression mutants in maize

Rajani M. S, Mohamed F. Bedair, Hong Li, Stephen M. G. Duff

published 06 Dec 2021

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IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation

Murshed H. Sarkar, Ryoji Yagi, Yukihiro Endo, Ryo Koyama-Nasu, Yangsong Wang, Ichita Hasegawa, Toshihiro Ito, Ilkka S. Junttila, Jinfang Zhu, Motoko Y. Kimura, Toshinori Nakayama

published 22 Nov 2021

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Leucine rich amelogenin peptide prevents ovariectomy-induced bone loss in mice

Naoto Haruyama, Takayoshi Yamaza, Shigeki Suzuki, Bradford Hall, Andrew Cho, Carolyn W. Gibson, Ashok B. Kulkarni

published 15 Nov 2021

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Silencing GhJUB1L1 (JUB1-like 1) reduces cotton (Gossypium hirsutum) drought tolerance

Qian Chen, Chaoya Bao, Fan Xu, Caixia Ma, Li Huang, Qigao Guo, Ming Luo

published 05 Nov 2021

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