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Genetically modified animals

Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice

Richard J. Epstein, Frank P. Y. Lin, Robert A. Brink, James Blackburn

Preclinical trials in Alzheimer’s disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

Mahvish Faisal, Jana Aid, [ ... ], Miriam A. Hickey

In vitro spermatogenesis in isolated seminiferous tubules of immature mice

Xuemin Feng, Takafumi Matsumura, [ ... ], Takehiko Ogawa

A seeding-based neuronal model of tau aggregation for use in drug discovery

Ines S. Amorim, Sylvie Challal, [ ... ], Patricia Machado

High signal-to-noise imaging of spontaneous and 5 ns electric pulse-evoked Ca²⁺ signals in GCaMP6f-expressing adrenal chromaffin cells isolated from transgenic mice

Ciara Viola, Thomas W. Gould, [ ... ], Gale L. Craviso

Mitotic CDK1 and 4E-BP1 II: A single phosphomimetic mutation in 4E-BP1 induces glucose intolerance in mice

Simon Cao, Michael J. Jurczak, [ ... ], Patrick S. Moore

Targeting nonsense-mediated RNA decay does not increase progranulin levels in the Grn ^R493X mouse model of frontotemporal dementia

Denise M. Smith, Michael L. Niehoff, [ ... ], Andrew D. Nguyen

Increased number of T cells and exacerbated inflammatory pathophysiology in a human IgG4 knock-in MRL/lpr mouse model

Yoshie Gon, Tsugumitsu Kandou, [ ... ], Hajime Yoshifuji

Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a^+/^- mouse model of Dravet syndrome

Lyndsey L. Anderson, Dilara A. Bahceci, [ ... ], Jonathon C. Arnold

Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model

Koya Obara, Kyoumi Shirai, [ ... ], Yasuyuki Amoh

Lack of the Ig cell adhesion molecule BT-IgSF (IgSF11) induced behavioral changes in the open maze, water maze and resident intruder test

Dirk Montag, Laura Pelz, Fritz G. Rathjen

Similarities and differences in constipation phenotypes between Lep knockout mice and high fat diet-induced obesity mice

Ji Eun Kim, Ayun Seol, [ ... ], Dae Youn Hwang

Metabolic differences and differentially expressed genes between C57BL/6J and C57BL/6N mice substrains

Shino Nemoto, Tetsuya Kubota, Hiroshi Ohno

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