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Genetically modified animals

A Transgenic mouse tolerant to syngeneic cancer cells expressing truncated human epidermal growth factor receptor

Theresa Barberi, Rahila Khuroo, Alan D. Friedman

published 07 Aug 2026

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Overexpression of CD97 in intestinal epithelial cells attenuates LPS-induced pro-inflammatory cytokine induction via stabilization of β-catenin early in life

Niklas Dressler, Steffi Mayer, Thomas Wiemers, Florentine Weise, Xiaoyan Feng, Gabriela Aust, Nicole Peukert, Martin Lacher, Jan Riedel

published 30 Jul 2026

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Neuromuscular ultrasound as a biomarker in the SOD1 mouse model of amyotrophic lateral sclerosis

Camilla Wohnrade, Nadine Thau-Habermann, Thomas Gschwendtberger, Julia Rückoldt, Zhong Huang, Stefanie Schreiber, Kirsten Haastert-Talini, Susanne Petri

published 14 Jul 2026

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Germline-mediated ubiquitous recombination in ScxCre male mice: Implications for tendon research

Haiyin Li, Christopher L. Mendias, Chike Cao

published 13 Jul 2026

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Role and mechanism of nitric oxide-regulated cGAS/STING pathway-mediated inflammatory response in hypoglycemia-induced coronary artery endothelial cell injury

Wenping Luo, Xiao Wei, Qian Xiao

published 26 Jun 2026

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Mitochondrial oxidative stress promotes the accumulation of advanced glycation end products

Firoz Akhter, Sourav Samanta, Alexandre A. Sosunov, Huawei Wu, Ethan Kim Tieu, Shi Fang Yan, Shirley ShiDu Yan

published 23 Jun 2026

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Bone marrow CCR3 dictates eosinophil lineage commitment of CD34⁺ progenitors to orchestrate allergic rhinitis: A composite study

Zhi-qiang Zhang, Meng-yi Wei, Jia-le Bei, Jing-yang Li, Mei-na Dai, Yin-li Jiang, Ya-ting Xiao, Ying Zhang, Xinhua Zhu

published 22 Jun 2026

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Neutrophil extracellular traps in the animal model of adenine-induced chronic kidney disease

Alexandra Gaál Kovalčíková, Gabriela Forraiová, Nelia Korotushak, Veronika Borbélyová, Diana Vavrincová-Yaghi, Peter Vavrinec, Ľudmila Podracká, Peter Celec

published 05 Jun 2026

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Significance of RGS13 expression in lupus B cells

Tomoya Nakajima, Koji Kitagori, Sohei Funakoshi, Mirei Shirakashi, Ryosuke Hiwa, Hideaki Tsuji, Shuji Akizuki, Ran Nakashima, Akio Morinobu, Hajime Yoshifuji

published 08 May 2026

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Poldip2 deficiency attenuates lung disease severity in a mouse model of COVID-19

Ruinan Hu, Alejandra Valdivia, Taylor White, Willy Ju, Maegan L. Brockman, Zhan Zhang, Hongyan Qu, Georgette Gafford, Giji Joseph, Samantha Burton, Leda Bassit, Tysheena P. Charles, Raymond F. Schinazi, Rebecca D. Levit, Cynthia A. Derdeyn, Kathy K. Griendling, Bernard Lassègue, Marina S. Hernandes

published 29 Apr 2026

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ATRX function beyond hippocampal CA1 is required for cognitive deficits in mouse models of intellectual disability

Julia T. Brott, Nathalie G. Bérubé

published 28 Apr 2026

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Ectopic expression of Aspergillus flavus uricase and URAT1 in therapeutic cells promotes intracellular degradation of uric acid in hyperuricemic mice

Yuzhong Feng, Jiazhen Cui, Xuan Huang, Yupeng Li, Haolong Dong, Xianghua Xiong, Gang Liu, Qingyang Wang, Huipeng Chen

published 20 Apr 2026

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Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline

Shweta Tendulkar, Tong Wu, Amy Strickland, Amber R. Hackett, Yurie Sato-Yamada, Xianrong Mao, Yo Sasaki, Jeffrey Milbrandt, A. Joseph Bloom, Aaron DiAntonio

published 17 Apr 2026

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