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DNA repair

Design and in silico validation of donor DNA for RNA-guided recombinase-mediated knockout of mstnb gene in Labeo rohita

Lukram Sushil Singh, Porkodi Murugesan, Gowhar Iqbal, Nagavara C. Nidarshan, Harini Gunasekaran, Ad. Viralkumar, Kiran D. Rasal, Manoj P. Brahmane, Sunil K. Nayak, Arvind A. Sonwane, Mukunda Goswami

published 15 Jul 2026

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DNA barcoding of Austrian terrestrial isopods (Crustacea: Isopoda: Oniscidea) reveals potential cryptic diversity

Anna-Chiara Barta, Luise Kruckenhauser, Hedda Büttner, Matthäus Greilhuber, Klaus Hasenhütl, Stephan Koblmüller, Lukas Kremp, Oliver Macek, Hanna Sommer, Nikolaus U. Szucsich, Martin Schwentner

published 06 Jul 2026

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Thymidylate synthase inhibitory drugs induce p53-dependent pathways differently

Eszter Holub, Milda Blanka Szajkó, Anna Felföldi, Beáta G. Vértessy, Angéla Békési

published 01 Jul 2026

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FGFR2 and favorable survival outcomes in resected poorly cohesive cell gastric cancer: Analysis from FGFR2 protein overexpression and genetic variation

Yun Ji Lee, Inuk Jung, Jin Ho Baek, Jong Gwang Kim, Ki Bum Park, Ji Yeon Park, Oh Kyoung Kwon, An Na Seo, Moonsik Kim, Byung Woog Kang

published 01 Jun 2026

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Non-viral in vivo electroporation-based chromosomal engineering and repair assessment in the murine uterine epithelium

Satoru Iwata, Yumi Miura, Takashi Iwamoto

published 11 May 2026

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Differential sensitivity of MCPH1- and BRCA2-deficient cancer cells to PARP-1 inhibition

Isobel G. Chapman, Xueqin Wu, Stephany Veuger, Paul A. Jowsey

published 03 Apr 2026

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HIF1α mediates resistance to radiation and to KRAS inhibitors in pancreatic adenocarcinoma

Kevin J. Tu, Sanjit K. Roy, Tami J. Kingsbury, Hem D. Shukla

published 26 Mar 2026

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HMGB1 reduce DNA damage by binding KU70 to activate NHEJ pathway in colorectal cancer cells after radiation

Xiuxin Liu, Yuhui Han, Ruixue Kuang, Wenjiong Sheng, Yan Zhang, Xinyu Jia, Xiaoxiao Gao, Yanchao Ma

published 24 Mar 2026

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Differential modulation of haematopoietic and oxidative injury by PARP-1 and ATR kinase inhibition in a murine model of acute irradiation

Baydaa Taher Sih

published 06 Mar 2026

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A damage-structured PDE model of stem cell hierarchies: The dual role of dedifferentiation in tissue homeostasis and aging

Louis Shuo Wang, Jiguang Yu, Zonghao Liu

published 24 Feb 2026

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Omics-aided design genome editing strategy for challenging human immortalized cell models

Patricia Mendoza-Garcia, Benjamin Keith, Markus Nordberg, Ella Quist, Cristina Ferrás, Ghaith M. Hamza, Ramy Elgendy, Stephanie Kay Ashenden, Jordi Chi, Natalie R. van Zuydam, Neil Hattersley, Xiang Zhang

published 12 Feb 2026

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Increased sensitivity of etoposide-treated breast cancer cells with an ATM inhibitor

Arun R. K. Kumar, Crystal Sara Shaji, Aswathi Rajagopalan, Sombodhi Bhattacharya, Wilner Martínez-López, Radha Saraswathy

published 20 Jan 2026

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Predicting the influence of homologous recombination repair deficiency genes on glioma heterogeneity and patient prognosis using multi-omics analysis and machine learning

Xin Wu, Longyuan Li, Zheng Zhan, Mei Chang, Jiaxuan Li, Zhouqing Chen, Zhong Wang

published 19 Dec 2025

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