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Clinical trials

Combined repetitive transcranial magnetic stimulation and functional electrical stimulation cycling to improve lower extremity function following incomplete spinal cord injury: Protocol for a pilot randomized controlled trial

Fereshteh Ghahremani, Siobhan Schabrun, Sue Peters, Laura Brunton, Janelle Unger

published 19 Mar 2026

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Effect of accentuated eccentric loading countermovement jumps and drop jump training with ladder training versus ladder training alone on sprint performance and change of direction ability in futsal players: A randomized controlled trial protocol

Darpan Chaudhari, Swapnil U. Ramteke

published 19 Mar 2026

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Helping primary care providers recognize and respond to medication non-adherence and drug-drug interactions: A randomized-controlled clinical utility trial in a value-based care setting

Trever Burgon, David Paculdo, Joshua Schrecker, Kelsy Gibson Ferrara, Randy E. David, Steven Johnson, Czarlota Valdenor, John W. Peabody

published 16 Mar 2026

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A pilot randomized controlled trial to explore the feasibility of a peer-delivered single-session brief intervention for youth with moderate risk substance use

Florence Jaguga, Matthew Turissini, Edith Kamaru Kwobah, Edith Apondi, Leslie A. Enane, Julius Barasa, Gilliane Kosgei, Yvonne Olando, Mary A. Ott, Allan Kimaina, Matthew C. Aalsma

published 16 Mar 2026

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Study protocol for a feasibility randomised controlled trial of MOVE SMART—An intervention to increase physical activity, reduce sedentary behaviour and improve health outcomes in patients with psoriasis

Gladys Onambele-Pearson, Ben Ives, Ishani Khosla, Rozemarijn Witkam, Matthew Roberts, Lucy Moorhead, Emma Bedson, Russ Cowper, Girvan Burnside, Helen S. Young

published 16 Mar 2026

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The effect of exercise intervention on atherosclerosis prevention in overweight or obese adults: A Bayesian network meta-analysis of randomized controlled trials

ChunBaiXue Yang, Yang Xu, XiuPeng Li, HangLin Yu, MingRui Wang, Bing Yang

published 13 Mar 2026

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The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol

Loice Achieng Ombajo, Joseph Nkuranga, Jeremy Penner, Emily Wangui Kamau, Nalia Ismael, Patricia Munseri, Irene Ayakaka, Niklaus Labhardt, Dalton Wamalwa, Patricia Ramgi, Raquel Matavele Chissumba, James Wagude, Muhammad Bakari, Victor Omodi, Edwin Otieno, Lisa Abuogi, Rena Patel, Charles Opondo, Daniel Grint, Leonard King’wara, AnneMarie Macharia, Andrew Mulwa, Patrick Amoth, on behalf of the Ndovu study group

published 13 Mar 2026

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Cure rate estimation with insufficient follow-up: A median-based bootstrap correction approach

Yumiko Ibi, Takashi Omori

published 12 Mar 2026

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Parental attitudes to randomised controlled trials in primary dental care: A qualitative study

Heather Coventry, Anne Maguire, Elaine McColl, Catherine Haighton

published 12 Mar 2026

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Intravenous thrombolysis for acute central retinal artery occlusion: Protocol for a systematic review and individual participant data meta-analysis of randomized controlled trials

Brian Mac Grory, Cécile Preterre, Pierre Lebranchu, Stephen James Ryan, Øystein Kalsnes Jørstad, Morten Carstens Moe, Johannes Tünnerhoff, Martin S. Spitzer, Carsten Grohmann, Oana M. Dumitrascu, Valérie Biousse, Benoit Guillon, Anne Hege Aamodt, Sven Poli, Matthew Schrag, The Central Retinal ArterY OcclusioN (CRAYON) Collaborators

published 10 Mar 2026

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Tunneled peripherally inserted central catheter versus non-tunneled and its effects in clinical outcomes: A multicenter randomized clinical trial protocol

Rodrigo do Nascimento Ceratti, Knut Taxbro, Vineet Chopra, Leandro Augusto Hansel, Carolina Geske Salini, Ivana Duarte Brum, Marina Junges, Arlene Gonçalves dos Santos, Eneida Rejane Rabelo-Silva

published 10 Mar 2026

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Chest drain REgular FLushing in ComplIcated parapneumonic EFfusions and empyemas: Study protocol for the RELIEF randomized controlled trial

Taryn K. Boyle, Jennifer D. Duke, Gulmira Yermakhanova, Rafael Paez, Greta Bridwell, Ankush P. Ratwani, Kaele M. Leonard, Heidi Chen, Frank E. Harrell Jr, Robert J. Lentz, Fabien Maldonado, Najib M. Rahman, Samira Shojaee

published 05 Mar 2026

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The effect of NASM-based corrective exercises on lumbar lordosis angle and selected muscle activity in women with lower cross syndrome: A randomized clinical trial

Somayyeh Ghaffari, Seyed Mohammad Hosseini, Mehdi Gheitasi

published 04 Mar 2026

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