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Phase II clinical investigation

Effects of taurine supplementation on metabolic health and biological aging in healthcare workers: A protocol for a triple-blinded, Bayesian-optimized phase II randomized controlled trial

Mandy H. M. Chu, Jacky K. M. Lai, [ ... ], Kwok M. Ho

Co-developing a survey on public understanding of sustainable clinical research: A study protocol

Dylan Keegan, Linda O’Neill, Peter Doran

Nasal steroids, irrigation, oral antibiotics, and subgroup targeting for effective management of acute sinusitis (NOSES): Protocol for a comparative effectiveness randomized controlled trial

Daniel Merenstein, Nawar Shara, [ ... ], Mihriye Mete

The effects of vaginal gel from Myrtus communis on the sexual function of married women during reproductive aging: A study protocol for a randomized controlled trial

Bahareh khajehpour, Raheleh Babazadeh, [ ... ], Malihe Mahmoudinia

Adaptation and evaluation of a digital dialectical behaviour therapy for youth at clinical high risk for psychosis: A protocol for a feasibility randomized controlled trial

Thea Lynne Hedemann, Yun Lu, [ ... ], Muhammad Omair Husain

Comparing the impact of systemic pituitary adenylate-cyclase-activating polypeptide (PACAP) and calcitonin gene-related peptide (CGRP) on motion-induced nausea and balance behaviors in mice

Shafaqat M. Rahman, Abigail Dweh, Anne E. Luebke

The efficacy and safety of lignocaine-embedded dissolvable microneedle versus EMLA for topical analgesia in adults undergoing venepuncture: A single-centre, parallel-group, double-blind randomised clinical trial protocol in a tertiary care setting

Muhammad Irfan Abdul Jalal, Mun Yin Yen, [ ... ], Fook-Choe Cheah

Personal approach for cancer treatment: A meta-analysis of Phase II clinical trials

Mikhail B. Potievskiy, Elena P. Zharova, [ ... ], Peter V. Shegai

Synergistic Treatment with Antiretrovirals and Laser Interstitial Thermal ThErapy (STARLITE) for unresectable glioblastoma: A phase 1 study protocol

Manav Daftari, Christian K. Ramsoomair, [ ... ], Ashish H. Shah

Modification of the nuclear pleomorphism score in the Modified Bloom-Richardson grading for invasive breast cancer

Azam Hilmi Mohd Zain, Seoparjoo Azmel Mohd Isa, [ ... ], Syed Sana Abrar

MDMA-assisted therapy and current treatment options for chronic, treatment-resistant, moderate or higher severity post-traumatic stress disorder: Systematic literature review

Filip Stanicic, Vladimir Zah, [ ... ], Debra de Angelo

Cost-effectiveness of the rural lifestyle eating and activity program (Rural LEAP)

Tiffany A. Radcliff, Murray J. Côté, [ ... ], Michael G. Perri

Protocol for evaluation of a virtual wheelchair simulator in assessing mobility skills and cognitive abilities in diverse populations: A multicentric mixed-methods pilot study

Débora Pereira Salgado, Caroline Valentini de Queiroz, [ ... ], Sheila Fallon

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