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Clinical trials

Evaluating the feasibility and acceptability of home-based isometric exercise and behaviour change for the management of hypertension: The HOME-FIT study protocol

Helen Llewellyn, Sarah Audsley, [ ... ], Gabriel Grizzo Cucato

Evaluating large language model performance in Risk of Bias assessments: A cross-sectional validation study

Siddharth Gandhi, Arveen Shokravi, Yashan Chelliahpillai, Michael Balas

Effectiveness and safety of intra-articular hyaluronic acid SEMICAL GEL-B CROSS therapy in knee osteoarthritis (SEM-ART1): Study protocol for a randomized, placebo controlled, double-blind, cross-over clinical trial

Meral Bilgilisoy Filiz, Hanife Hale Hekim, Ahmet Bal, Aslıhan Kara

Evaluating a sexual violence primary prevention program in Australian secondary schools: A protocol for a pilot cluster randomised controlled trial

Freda Haylett, Jacqueline Kuruppu, [ ... ], Leesa Hooker

Optimizing treatment for depressed parents of children with emotional and behavioral disorders: A multi-site feasibility trial

Brendan F. Andrade, Sabrina Brodkin, [ ... ], Peter Szatmari

Pascal selective laser trabeculoplasty (PSLT) in the treatment of ocular hypertension and open-angle glaucoma compared to travoprost eye drops: A non-inferiority clinical trial

Rafaela C. M. C. de Almeida, Rodrigo L. Lindenmeyer, [ ... ], Helena M. Pakter

Effects of immersive virtual reality on limb motor function, balance, gait and quality of life after stroke: A systematic review and meta-analysis

Dana Islam, Ingela Marklund, Mia von Euler, Maria Jaensson

Protocol for the SACLA trial: Efficacy and safety of subretinal monteplase for submacular hemorrhage in a phase II single-arm multicenter decentralized clinical trial

Noriko Yoshida, Yuko Kobayakawa, [ ... ], Hiroshi Enaida

Ketogenic diet therapies for the treatment of drug-resistant epilepsy in children and adults: A systematic review

María Magdalena Vaccarezza, Verónica Laura Sanguine, Giselle Balaciano

Monotherapy or combinations? Intravenous vitamin C in sepsis and septic shock: An umbrella review of 31 systematic reviews

Víctor Juan Vera-Ponce, Jhosmer Ballena-Caicedo, [ ... ], Mario J. Valladares-Garrido

Effects of transcutaneous auricular vagus nerve stimulation combined with repetitive facilitative exercise on lower limb motor function in patients with intracerebral hemorrhage: A pilot randomized controlled trial

Hanji Chen, Hanbo Chen, [ ... ], Mengyun Li

Incidence of depression in patients with psoriasis and psoriatic arthritis treated with biologic therapy: Protocol for a systematic review and meta-analysis

Emily Sirotich, Weston Lowry, [ ... ], Jeffrey M. Cohen

Determinants of dropout from lifestyle interventions for overweight polycystic ovary syndrome: An exploratory analysis of randomized controlled trial

Min Xie, Siyu Zhou, [ ... ], Jing Zhang

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