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Cancer genomics

HCLmNet: A unified hybrid continual learning strategy multimodal network for lung cancer survival prediction

MD Ilias Bappi, David J. Richter, Shivani Sanjay Kolekar, Kyungbaek Kim

published 24 Mar 2026

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A multiple filter-wrapper feature selection algorithm based on process optimization mechanism for high-dimensional omics data analysis

Yongtao Shi, Yuefeng Zheng, Xiaotong Bai

published 11 Dec 2025

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Biologically-informed regional subset analysis with CatBoost for robust tissue-of-origin prediction

Sungmin Yang, Hong-Gee Kim

published 04 Dec 2025

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Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples

Wenshu Li, Jeffrey A. Leibowitz, Shuoguo Wang, Louisa Walker, Chang Xu, Kuei-Ting Chen, Alexa B. Schrock, Jason Hughes, Nimesh Patel, Julia A. Elvin, Lauren L. Ritterhouse, Ethan Sokol, Garrett Frampton, Lucas Dennis, Bahar Yilmazel, Brennan Decker

published 17 Nov 2025

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In vivo investigation of STN1 downregulation in melanoma formation in adult mice following UV irradiation

Sara Knowles, Fang Wang, Maarten C. Bosland, Shobhan Gaddameedhi, Weihang Chai

published 14 Nov 2025

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Personal approach for cancer treatment: A meta-analysis of Phase II clinical trials

Mikhail B. Potievskiy, Elena P. Zharova, Lidia A. Nekrasova, Airat I. Garifullin, Ivan V. Korobov, Nikita E. Shevchenko, Anastasia A. Zabolotneva, Dmitriy N. Atochin, Andrei D. Kaprin, Peter V. Shegai

published 26 Sep 2025

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Evaluation of therapeutic agent selection based on comprehensive genomic profiling in gastroenteropancreatic neuroendocrine neoplasms

Suguru Miyazawa, Hiroaki Ono, Hironari Yamashita, Daisuke Asano, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Satoru Aoyama, Naoya Ishibashi, Keiichi Akahoshi, Sadakatsu Ikeda, Minoru Tanabe

published 06 Aug 2025

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Epigenome and three-dimensional genome architecture remodeling during NDM29-mediated retro-transformation of neuroblastoma cells

Francesca Baldini, Aldo Pagano, Lama Zeaiter, Paolo Bianchini, Hawraa Zbeeb, Alberto Diaspro, Laura Vergani

published 31 Jul 2025

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Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse

Ruiqing Fu, He Amy Su, Yi Zhao, Yafei Tian, Hongyan Chen, Daru Lu

published 15 Jul 2025

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Characterization and identification of extrachromosomal circular DNA in cholangiocarcinoma

Zar Zar Win, Hasaya Dokduang, Siriyakorn Kulwong, Watcharin Loilome, Nisana Namwat, Jutarop Phetcharaburanin, Thidathip Wongsurawat, Piroon Jenjaroenpun, Poramate Klanrit, Arporn Wangwiwatsin

published 05 May 2025

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Multi-omics evaluation of peritoneal fluid in gastroesophageal cancer (OMEGCA): protocol for a prospective multicentre cohort study to detect occult peritoneal metastases in patients undergoing curative-intent treatment

David S. Liu, Zexi Allan, Jeanne Tie, Katheryn Hall, Margaret M. Lee, Darren J. Wong, Stephen Q. Wong, Niall C. Tebbutt, David I. Watson, Markus Trochsler, Krinal Mori, Nicole Winter, Sarah Martin, Geraldine Ooi, Yahya Al-Habbal, Ronald Ma, Nicholas J. Clemons

published 16 Apr 2025

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Harmonizing and integrating the NCI Genomic Data Commons through accessible, interactive, and cloud-enabled workflows

Ling-Hong Hung, Bryce Fukuda, Robert Schmitz, Varik Hoang, Wes Lloyd, Ka Yee Yeung

published 04 Mar 2025

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Integrative analysis of SEPN1 in glioma: Prognostic roles, functional implications, and potential therapeutic interventions

Zisong Wang, Danwen Wang, Xuanyu Wang, Yihang Xu, Yunhe Yuan, Yuxin Chen, Zhiqiang Li, Xiaoping Liu

published 07 Feb 2025

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