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Cancer genomics

Benchmark of biomarker identification and prognostic modeling methods on diverse censored data

Wesley Fletcher, Samiran Sinha

published 16 Jun 2026

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A fusion-deletion genomic-event underlies poor prognosis in young patients with luminal breast cancer

Le-Wei Zheng, Yi-Ming Liu, Ke-Da Yu, Cui-Cui Liu

published 16 Jun 2026

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Tumor hypoxia is associated with global copy-number alteration burden and subtype-dependent overall survival in breast cancer: Evidence from TCGA and METABRIC

Wenhan Yang

published 02 Jun 2026

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HCLmNet: A unified hybrid continual learning strategy multimodal network for lung cancer survival prediction

MD Ilias Bappi, David J. Richter, Shivani Sanjay Kolekar, Kyungbaek Kim

published 24 Mar 2026

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A multiple filter-wrapper feature selection algorithm based on process optimization mechanism for high-dimensional omics data analysis

Yongtao Shi, Yuefeng Zheng, Xiaotong Bai

published 11 Dec 2025

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Biologically-informed regional subset analysis with CatBoost for robust tissue-of-origin prediction

Sungmin Yang, Hong-Gee Kim

published 04 Dec 2025

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Analytical validation of a homologous recombination deficiency signature (HRDsig) in pan-tumor tissue samples

Wenshu Li, Jeffrey A. Leibowitz, Shuoguo Wang, Louisa Walker, Chang Xu, Kuei-Ting Chen, Alexa B. Schrock, Jason Hughes, Nimesh Patel, Julia A. Elvin, Lauren L. Ritterhouse, Ethan Sokol, Garrett Frampton, Lucas Dennis, Bahar Yilmazel, Brennan Decker

published 17 Nov 2025

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In vivo investigation of STN1 downregulation in melanoma formation in adult mice following UV irradiation

Sara Knowles, Fang Wang, Maarten C. Bosland, Shobhan Gaddameedhi, Weihang Chai

published 14 Nov 2025

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Personal approach for cancer treatment: A meta-analysis of Phase II clinical trials

Mikhail B. Potievskiy, Elena P. Zharova, Lidia A. Nekrasova, Airat I. Garifullin, Ivan V. Korobov, Nikita E. Shevchenko, Anastasia A. Zabolotneva, Dmitriy N. Atochin, Andrei D. Kaprin, Peter V. Shegai

published 26 Sep 2025

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Evaluation of therapeutic agent selection based on comprehensive genomic profiling in gastroenteropancreatic neuroendocrine neoplasms

Suguru Miyazawa, Hiroaki Ono, Hironari Yamashita, Daisuke Asano, Yoshiya Ishikawa, Shuichi Watanabe, Hiroki Ueda, Satoru Aoyama, Naoya Ishibashi, Keiichi Akahoshi, Sadakatsu Ikeda, Minoru Tanabe

published 06 Aug 2025

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Epigenome and three-dimensional genome architecture remodeling during NDM29-mediated retro-transformation of neuroblastoma cells

Francesca Baldini, Aldo Pagano, Lama Zeaiter, Paolo Bianchini, Hawraa Zbeeb, Alberto Diaspro, Laura Vergani

published 31 Jul 2025

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Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse

Ruiqing Fu, He Amy Su, Yi Zhao, Yafei Tian, Hongyan Chen, Daru Lu

published 15 Jul 2025

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Characterization and identification of extrachromosomal circular DNA in cholangiocarcinoma

Zar Zar Win, Hasaya Dokduang, Siriyakorn Kulwong, Watcharin Loilome, Nisana Namwat, Jutarop Phetcharaburanin, Thidathip Wongsurawat, Piroon Jenjaroenpun, Poramate Klanrit, Arporn Wangwiwatsin

published 05 May 2025

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